calcipotriene


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Related to calcipotriene: Calcitriol, Tazarotene, Calcipotriol

calcipotriene

 [kal″sĭ-po-tri´ēn]
a synthetic derivative of cholecalciferol (vitamin D3), applied to the skin to treat psoriasis.

calcipotriene

A topical vitamin-D analogue with minimum effects on vitamin-D metabolism, which is FDA-approved for treating mild-to-moderate psoriasis; it is similar in efficacy to topical corticosteroids.

Adverse effects
Rarely, hypercalcaemia.
References in periodicals archive ?
Additionally, the FDA approved Taclonex (calcipotriene and betamethasone dipropionate) Topical Suspension in the topical treatment of scalp and body plaque psoriasis in patients 12 years and older.
Calcipotriene 0.005%/betamethasone dipropionate 0.064% formulated using this technology was developed as a cream with rapid absorption and cosmetic acceptability.
The US Food and Drug Administration (FDA) has approved Australia-based Mayne Pharma Group Limited's (ASX: MYX) SORILUX (calcipotriene) Foam, 0.005% to treat adolescents, it was reported yesterday.
According to the company, SORILUX Foam contains calcipotriene, a synthetic vitamin D analog that has a similar receptor binding affinity as natural vitamin D.
Calcipotriene is a synthetic analogue of vitamin D3 (calcipotriol) and it has been shown to have immunosuppressive and immunomodulating properties.
A new scalp formulation of calcipotriene plus betamethasone compared with its active ingredients and the vehicle in the treatment of scalp psoriasis: a randomized, double-blind, controlled trial.
Others include the asthma remedy terbutaline, the psoriasis medication calcipotriene and a numbing agent, prilocaine/lidocaine.
Treatment of Nevus comedonicus with topical tazarotene and calcipotriene. J Drugs Dermatol 2004; 3:674-676.
-- A four-day topical combination regimen of 5-fluorouracil (5-FU) and calcipotriene removed almost 90% of facial actinic keratoses--significantly more than with 5-FU monotherapy, in a randomized, double-blind controlled study.
Second-line treatments for those who need an alternative to steroids include topical calcineurin inhibitors, such as tacrolimus or pimecrolimus, the synthetic vitamin D cream calcipotriene, and topical retinoids.
The impact of calcipotriene on light phototherapy is contentious and requires further research.