calbindin-D28k

calbindin-D28k

A calcium-binding protein encoded by CALB1, which is found in the kidney and neuroendocrine cells of the cerebellum and elsewhere. It has four EF-hand-type calcium-binding domains along its single 263-residue chain. It mediates calcium absorption which, in the brain, occurs independent of vitamin D.
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Se ha sugerido que estos tumores son originados de celulas progenitoras de la matriz del ventriculo, fundamentandose en el analisis de la expresion de Calbindin-D28K. Los meduloblastomas clasicos aparecen predominantemente en el vermis cerebeloso.
Vigot, "Cytoplasmic calcium buffer, calbindin-D28k, is regulated by excitatory amino-acids," NeuroReport, vol.
Relationship between calbindin-D28K in the A and B cells of rat endocrine pancreas and secretion of insulin and glucagon: Influence of vitamin D3deficiency and 1, 25 dihydroxyvitamin [D.sub.3].
Calcium-binding protein (calbindin-D28K) and parvalbumin immunocytochemistry in the normal and epileptic human hippocampus.
Cerebellar Purkinje cells are reduced in a subpopulation of autistic brains: a stereological experiment using calbindin-D28k. Cerebellum, 7(3):406-16, 2008.
Gene cloning, sequencing and eukaryotic expression plasmid construction of chicken calbindin-D28k Chin J Anim Vet Sci 2008;39:1329-35.
Laxer, "Calcium-binding protein (calbindin-D28K) and parvalbumin immunocytochemistry in the normal and epileptic human hippocampus," Journal of Comparative Neurology, vol.
(11) Furthermore, 1,25 [(OH).sub.2]D3 is believed to be vital for insulin exocytosis by increasing the expression of calbindin-D28K in [beta]-cells.
Loss of calbindin-D28K is associated with the full range of tangle pathology within basal forebrain cholinergic neurons in Alzheimer's disease.
Blatt, "Cerebellar Purkinje cells are reduced in a subpopulation of autistic brains: a stereological experiment using calbindin-D28k," Cerebellum, vol.
Expression of calbindin-D28k in C6 glial cells stabilizes intracellular calcium levels and protects against apoptosis induced by calcium ionophore and amyloid beta-peptide.
The expression of calbindin-D28K (vitamin D dependent on the union of proteins and calcium) has demonstrated a protective effect on beta cells from cytokine mediated cell death, reducing the risk of T2DM [88].