S100G

(redirected from calbindin D9K)

S100G

A gene on chromosome Xp22.2 that encodes calbindin-D9K, a cytosolic vitamin D-dependent calcium-binding protein, which contains 2 active calcium-binding domains. Calbindin D9K’s expression correlates with calcium transport activity; it may increase Ca2+ absorption by buffering Ca2+ in the cytoplasm and increase ATP-dependent Ca2+ transport in duodenal basolateral membrane vesicles.
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Immunocytochemical and In situ hybridization studies of the distribution of calbindin D9k in the bovine placenta throughout pregnancy.
Relationship of vitamin D with calbindin D9k and D28k expression in ameloblasts.
The reason for this change can be reduction of the negative net charge on the calcium sensor, as observed for calcium binding by calbindin D9k (Kesvatera et al.