References in periodicals archive ?
Although classical MAS is characterized with fibrous dysplasia, cafe au lait spots on the skin and excessive function in the endocrine glands (frequently early puberty), some patients may be manifested with different endocrine involvements (1).
Other clinical features such as seizures, skin nodules, dermal neurofibromas, cafe au lait spots (much less common than in NF1).
While the disorder ultimately may be associated with neurologic, ocular, skeletal, and other manifestations, cafe au lait spots often are the only clinical finding in infancy.
A special type of polyostotic fibrous dysplasia is McCune-Albright syndrome, which is associated with precocious sexual development and cafe au lait spots on the skin.