cafe au lait spots


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia.
Related to cafe au lait spots: neurofibromatosis

ca·fé au lait spots

pigmented cutaneous lesions, ranging from light to dark brown, and due to an excess of melanosomes in the malpighian cells, rather than to an excess of melanocytes; café au lait spots are one of the major cutaneous manifestations of neurofibromatosis (von Recklinghausen disease); six or more café au lait spots, some exceeding 1.5 cm in diameter, can almost always be found in type 1 (peripheral) neurofibromatosis. These are often accompanied by frecklelike spots in the axilla.

ca·fé au lait spots

(kăf-ā-ō-lā spotz)
Pigmented cutaneous lesions, ranging from light to dark brown; due to an excess of melanosomes in the malpighian cells, rather than to an excess of melanocytes.

cafe au lait spots

Milk coffee-coloured oval patches, from one to 15cm or more long, on the skin. If more than five of these occur in childhood, and especially if they extend into the armpit, it is likely that the condition of NEUROFIBROMATOSIS (Recklinghausen's disease) is developing.

café au lait spots

uniformly light-brown, sharply defined, ovoid areas of skin pigmentation, especially of axillary skin, characteristic of neurofibromatosis (see disease, von Recklinghausen's )
References in periodicals archive ?
Although classical MAS is characterized with fibrous dysplasia, cafe au lait spots on the skin and excessive function in the endocrine glands (frequently early puberty), some patients may be manifested with different endocrine involvements (1).
Other clinical features such as seizures, skin nodules, dermal neurofibromas, cafe au lait spots (much less common than in NF1).
While the disorder ultimately may be associated with neurologic, ocular, skeletal, and other manifestations, cafe au lait spots often are the only clinical finding in infancy.
A special type of polyostotic fibrous dysplasia is McCune-Albright syndrome, which is associated with precocious sexual development and cafe au lait spots on the skin.