cafe au lait spots


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Related to cafe au lait spots: neurofibromatosis

ca·fé au lait spots

pigmented cutaneous lesions, ranging from light to dark brown, and due to an excess of melanosomes in the malpighian cells, rather than to an excess of melanocytes; café au lait spots are one of the major cutaneous manifestations of neurofibromatosis (von Recklinghausen disease); six or more café au lait spots, some exceeding 1.5 cm in diameter, can almost always be found in type 1 (peripheral) neurofibromatosis. These are often accompanied by frecklelike spots in the axilla.

ca·fé au lait spots

(kăf-ā-ō-lā spotz)
Pigmented cutaneous lesions, ranging from light to dark brown; due to an excess of melanosomes in the malpighian cells, rather than to an excess of melanocytes.

cafe au lait spots

Milk coffee-coloured oval patches, from one to 15cm or more long, on the skin. If more than five of these occur in childhood, and especially if they extend into the armpit, it is likely that the condition of NEUROFIBROMATOSIS (Recklinghausen's disease) is developing.
References in periodicals archive ?
Multiple cafe au lait spots on his body in addition to the classic mucocutaneous macules around the mouth and the buccal mucosa was another unusual finding.
Cafe au lait spots with irregular borders with long diameters of 15x20 cm, 5X11 cm and 10X15 cm were present on the left shoulder and neck (Figure 1).
* six or more cafe au lait spots Greater than 5 mm (prepubertal) and Greater than 15 mm (postpubertal) in diameter
The typical clinical picture of NF1, which is usually identifiable at a glance, consists of multiple hemmed-in areas of increased skin pigmentation (cafe au lait spots), accompanied by dermal and neural tumors of various types.