cadherins


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cadherins

A family of calcium-dependent adhesion molecules found on the surface of cells. Cadherins are trans-membrane glycoproteins that mediate cell to cell junctions and contribute to the maintenance of cell shape. Cadherins differ in molecular weight at different locations, ranging from 120 to 135Kd.
References in periodicals archive ?
(b) N- cadherin is strongly present; (c-f) extracellular matrix typical markers of cartilage are shown throughout the spheroid area; (c) collagen type II; (d) collagen type VI; (e) aggrecan; (f) chondroitin sulfate.
Cadherins are thus a diverse class of molecules involved in many physiological functions, with diverse tissue-specific distributions [76].
Bryan, "Cell adhesion and urothelial bladder cancer: the role of cadherin switching and related phenomena," Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences, vol.
EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt.
Convergence of Wnt, [beta]-catenin, and cadherin pathways.
The observation that cadherins play an important role in the establishment of the epithelial phenotype, cell migration, cell differentiation, and tumor dissemination has stimulated great interest in this family of adhesion molecules.
Testing for cadherins might be one of those methods.