Cadherins play distinctive roles in retinal regeneration.
Transcriptional regulation of
cadherins during development and carcinogenesis.
EPLIN mediates linkage of the
cadherin catenin complex to F-actin and stabilizes the circumferential actin belt.
Convergence of Wnt, [beta]-catenin, and
cadherin pathways.
The observation that
cadherins play an important role in the establishment of the epithelial phenotype, cell migration, cell differentiation, and tumor dissemination has stimulated great interest in this family of adhesion molecules.
While the direct link between
cadherins and chondrogenesis is not completely understood," Mauck said, "what's known is that if you enhance these interactions early during tissue formation, you can make more cartilage, and, if you block them, you get very poor cartilage formation.
While the direct link between
cadherins and chondrogencsis is not completely understood," Mauck said, "what's known is that if you enhance these interactions early during tissue formation, you can make more cartilage, and, if you block them, you get very poor cartilage formation.
Because their extracellular sites have an affinity for calcium,
cadherins (Calcium-dependent adhesion) play a central role in cell polarization and adhesion (30).
Rapid suppression of activated Racl by
cadherins and nectins during de novo cell-cell adhesion.
The classical
cadherins consist of E (epithelial), N (neuronal) and P (placental)
cadherin, which are the best studied representatives of this family.
Mueller and colleagues showed that reelin controls the function of
cadherins in nerve cells.
Specific topics include
cadherins and connexins in pulmonary endothelial function, pulmonary endothelial progenitor cells, oxidant-mediated signaling and injury in pulmonary endothelium, therapeutic strategies to limit pulmonary endothelial cell permeability, genetic insights into endothelial barrier regulation in the acutely inflamed lung, and collagen vascular diseases and pulmonary endothelium.
