CDH8

(redirected from cadherin-8)

CDH8

A gene on chromosome 16q22.1 that encodes a calcium-dependent cell–cell adhesion glycoprotein (cadherin), which is involved in regulating cell–cell adhesions, mobility and proliferation of epithelial cells. CDH8 is a so-called type-II (atypical) cadherin—which lacks a HAV cell adhesion recognition sequence specific to type-I cadherins—expressed in the brain; it is putatively involved in synaptic adhesion, axon outgrowth and guidance.
References in classic literature ?
Now Alec Carmichael was on the staff of half a dozen hospitals.
Soon after, the little boy was sent home, as Indian children always are, but his mother remained out in India, and a year or two later married Major Henry Carmichael Smyth.
Again, at Tristan d'Acunha in the Atlantic, Carmichael [6] states that the only two land-birds, a thrush and a bunting, were "so tame as to suffer themselves to be caught with a hand-net.