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Related to cacodylic: Cacodylic acid, dimethylarsinic acid


Relating to cacodyl; denoting especially cacodylic acid.
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Left ventricle myocardial and lung samples were homogenized in an icecold extraction buffer [23] (1: 10 wt/vol) containing cacodylic acid (10 mmol/L), NaCl (150 mmol/L), Zn[Cl.sub.2] (1 mmol/L), Ca[Cl.sub.2] (20 mmol/L), Na[N.sub.3] (1.5 mmol/L), and Triton X-100 0.01% vol/vol (pH 5).
The brains were washed by rinsing two times (30 min) with cacodylate buffer (0.2 M cacodylic acid [Na salt] in 0.3 M NaCl, pH 7.5), followed by two rinses (30 min) with 4% Triton X-100 in phosphate-buffered saline (PBS, consisting of 50 mM [Na.sub.2]HP[O.sub.4], 140 mM NaCl, pH 7.2).
More recently, inorganic forms have been replaced by organic arsenicals, such as disodium methylarsenate and cacodylic acid.
Science Issue Paper: Mode of Carcinogenic Action for Cacodylic Acid (Dimethylarsinic Acid, DMAV) and Recommendations for Dose Response Extrapolation.
The strength-of-evidence conclusion from the epidemiological studies included in the first report (IOM 1994) was for "inadequate/insufficient evidence to determine whether an association exists" between exposure to herbicides [2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) and its contaminant TCDD, cacodylic acid, and Picloram] and diabetes mellitus.