sprue

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sprue

 [sproo]
a chronic form of malabsorption syndrome occurring in both tropical and nontropical forms.
celiac sprue (nontropical sprue) celiac disease.
tropical sprue a chronic disease affecting the digestive system, marked by imperfect absorption of food elements, especially fat, xylose, and vitamin B12, from the small intestine. It is closely related to celiac disease and may be identical to it.



The name sprue derives from a Dutch word describing inflammation of the mouth, which is a frequent symptom. The disease has been recognized for more than 2000 years. It occurs mostly, but not exclusively, in the tropics.
Symptoms and Treatment. Symptoms are loss of appetite, flatulence, anemia, diarrhea, stomach cramps, and extreme loss of weight. Stools are usually pale, greasy, unformed, and foul-smelling, but at times become watery. If a deficiency of vitamin B complex is also present, cracks develop at the corners of the mouth and the tongue becomes smooth, glossy, and bright red.



Treatment consists of a special diet of foods that are low in fat and high in protein. Diets free of gluten, a viscid grain protein, may be prescribed. Liver preparations, folic acid, calcium lactate tablets, vitamin B12, and iron supplements to provide food elements that are not absorbed, as well as skim milk and ripe bananas, have produced favorable results. Antibiotics have proved temporarily successful, but their prolonged use is not recommended.

Cases of sprue that are recognized early respond better to treatment than do cases of long standing. Appetite and weight return rapidly. The time required for complete recovery is prolonged, however, especially in extreme cases.

sprue

(sprū),
1. Primary intestinal malabsorption with steatorrhea. Synonym(s): cachexia aphthosa
2. In dentistry, wax or metal used to form the aperture(s) for molten metal to flow into a mold to make a casting; also, the metal that later fills the sprue hole(s).
[D. spruw]

sprue

(spro͞o)
n.
A chronic, chiefly tropical disease characterized by diarrhea, emaciation, and anemia, caused by defective absorption of nutrients from the intestinal tract.

sprue

(sprū)
1. Primary intestinal malabsorption with steatorrhea.
2. dentistry Wax or metal used to form the aperture(s) through which molten metal flows into a mold to make a casting; also, the metal that later fills the sprue hole(s).
[D. spruw]

sprue

A disorder in which nutrients are poorly absorbed from the intestine. See also MALABSORPTION.

Sprue

A disorder of impaired absorption of nutrients from the diet by the small intestine (malabsorption), resulting in malnutrition. Two forms of sprue exist: tropical sprue, which occurs mainly in tropical regions; and celiac sprue, which occurs more widely and is due to sensitivity to the wheat protein gluten.

sprue

(sprū)
In dentistry, wax or metal used to form aperture(s) for molten metal to flow into a mold to make a casting; also, metal that later fills sprue hole(s).
[D. spruw]