CA.1ad.3(redirected from cAR3)
Also found in: Acronyms.
CA.1ad.3A gene on chromosome 8q21.2 that encodes a carbonic anhydrase, a zinc metalloenzyme that catalyses the reversible hydration of carbon dioxide. Carbonic anhydrases participate in various biological processes, including respiration, calcification, maintaining acid-base balance and bone resorption, as well as producing aqueous humour, cerebrospinal fluid, saliva and gastric acid. Carbonic anhydrase 3 is a glycosylphosphatidyl-inositol-anchored membrane isozyme, expressed on the luminal surfaces of pulmonary (and other) capillaries and proximal renal tubules; it is thought to have a role in hereditary defects in bicarbonate transport.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.