c-Mpl ligand

c-Mpl ligand

humoral compound that affects blood platelet production by stimulating megakaryocytes.
References in periodicals archive ?
Kaushansky, "The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl," The Journal of Biological Chemistry, vol.
Stefanovic, "Clinical use of thrombopoietin (c-Mpl ligand)," Medicinski Pregled, vol.
Thrombopoietin (TPO), also known as Megakaryocyte Growth and Development Factor (MGDF) or c-MpL ligand, is a hormone which is synthesized in the liver and dominantly regulates the process of megakaryocytopoiesis [8].
These agents act via c-MpL ligand mediated activation of the JAK-STAT and MAP kinase pathways [22, 23].
Grabarek, "Regulation of platelet activation in vitro by the c-Mpl ligand, thrombopoietin," Blood, vol.