butyrylcholinesterase


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BCHE

A gene on chromosome 3q26.1-2 that encodes butyrylcholinesterase, which has a broad substrate spectrum. It contributes to inactivation of the neurotransmitter acetylcholine and can degrade neurotoxic organophosphate esters.
 
Molecular pathology
Mutant alleles at BCHE are responsible for suxamethonium sensitivity.

plas·ma chol·ine·ste·rase

(plaz'mă kō'lin-es'tĕr-ās)
A type of cholinesterase found in plasma.
See also: fluoride number
Synonym(s): butyrylcholinesterase, pseudocholinesterase.

butyrylcholinesterase

the cholinesterase of plasma (a pseudocholinesterase), which is different from the cholinesterase of the myoneural junctions (acetylcholinesterase).
References in periodicals archive ?
Laser captured hepatocytes show association of butyrylcholinesterase gene loss and fibrosis progression in hepatitis C-infected drug users.
In vitro acetylcholinesterase and butyrylcholinesterase inhibitory potentials of Jatropha gossypifolia plant extracts," Acta Poloniae Pharmaceutica--Drug Research, vol.
Prospective of human butyrylcholinesterase as a detoxifying antidote and potential regulator of controlled-release drugs.
DNA mutation associated with the human butyrylcholinesterase K-variant and its linkage to the atypical variant mutation and other polymorphic sites.
CDT% was significantly associated or correlated in the hazardous drinking groups with BMI, HDL and LDL cholesterol, triglycerides, butyrylcholinesterase, smoking, and transferrin (see Table 2 in the online Data Supplement).
Compound 3 showed weak activities in DPPH assay and againstacetylcholinesterase and butyrylcholinesterase enzymes while moderate activity against LOX with IC50 96.
Arginine administration decreases cerebral cortex acetylcholinesterase and serum butyrylcholinesterase probably by oxidative stress induction.
Keywords: 2,4-Dihydroxyacetophenone, Hydrated hydrazine, Acid halides, a-Glucosidase, Butyrylcholinesterase.
Butyrylcholinesterase (BChE), which is less specific but more sensitive than AChE and is so called pseudocholinesterase.
The physiologic function of plasma cholinesterase remains unresolved, however, and it is not clear whether the known sequence variations in the butyrylcholinesterase gene (BCHE)5 account for all of the genetic variations in the population.
TARGETING BUTYRYLCHOLINESTERASE FOR ALZHEIMER'S DISEASE THERAPY
Keywords: Piperdine, analgesics, aectylcholinesterase, butyrylcholinesterase, neurotransmitters, a-amylase