butyrophenone


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butyrophenone

 [bu″tĭ-ro-fe´nōn]
any of a class of structurally related antipsychotic agents; the prototype is haloperidol.

butyrophenone

/bu·ty·ro·phe·none/ (bu″tĭ-ro-fe´nōn) any of a class of structurally related antipsychotic agents, including haloperidol.

butyrophenone

(byo͞o-tĭr′ō-fə-nōn′, byo͞o′tə-rō-)
n.
Any of a group of antipsychotic drugs, such as haloperidol, administered in the treatment of schizophrenia and other psychiatric disorders.

butyrophenone

[byo̅o̅′tərōfē′nōn]
one of a small group of major tranquilizers. They are used in treating psychosis, to decrease the choreic symptoms of Huntington's disease and the tics and coprolalia of Gilles de la Tourette's syndrome, and are used as an adjunct in neuroleptanesthesia. Principal butyrophenones are haloperidol and droperidol. Butyrophenones are pharmacologically and clinically similar to phenothiazines.

butyrophenone

a chemical class of major tranquilizers which includes droperidol and azaperone.
References in periodicals archive ?
The butyrophenone derivative droperidol is the most potent in this class and is the most effective drug for severe NVP and hyperemesis gravidarum.
The butyrophenone derivative droperidol is the most potent m this 'class nd is the most effective drug available for severe NVP and hyperemesis gravidarum.
In a double-blind, randomized trial involving a total of 147 patients who presented to an emergency department during the 2004-2005 study period, an intramuscular injection of 5 mg of the butyrophenone antipsychotic droperidol was found to result in significantly greater sedation after 15 and 30 minutes (as measured by mean scores on the Altered Mental Status Scale) than did 10 mg or 20 mg of the atypical antipsychotic ziprasidone (Geodon) or 2 mg of the benzodiazepine lorazepam.
Human studies have shown that the liver poisoned with Amantia phalloides, phenothiazines (antipsychotic drugs) and butyrophenones (antipsychotic drugs), silymarin reduces the hepatic damage.