butyrate paradox

butyrate paradox

A poorly understood phenomenon in which butyrate—which is produced by anaerobic fermentation by bacteria in the colon—inhibits colonic carcinoma cells and promotes healthy colonic epithelial cells. Some alternative healthcare providers regard this chemopreventive effect as evidence that butyrate can reverse colorectal cancer once it develops; there is no peer-reviewed data to support this claim.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.