The effects of buthionine sulfoximine
, diethyldithiocarbamate or 3-amino-1,2,4-triazole on propyl gallate-treated HeLa cells in relation to cell growth, reactive oxygen species and glutathione.
reported that injection of melatonin (4 mg/kg, ip) into newborn rats with developed cataracts by buthionine sulfoximine
as the inhibitor of glutathione synthesis decreased the incidence of cataract and increased the total glutathione levels significantly in the lens.
1 mM buthionine sulfoximine
(BSO) for 24 hr before the addition of Cr(VI) (DeLoughery et al.
The contribution of redox imbalance in MAL-A induced cytotoxicity was confirmed by pre-incubating cells with an antioxidant, N-acetyl-L-cysteine (NAC) or a thiol depletor, buthionine sulfoximine
Shock and kill" effects of class I-selective histone deacetylase inhibitors in combina- tion with the glutathione synthesis inhibitor buthionine sulfoximine
in cell line models for HIV-1 quiescence.
And the inhibitor of de novo GSH synthesis, buthionine sulfoximine
, is known to be able to produce oxidative stress.
Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine
Effects of buthionine sulfoximine
nifurtimox and benznidazole upon trypanothione and metallothionein proteins in Trypanosoma cruzi.
Liquiritigenin, an aglycone of liquiritin in Glycyrrhizae radix, prevents acute liver injuries in rats induced by acetaminophen with or without buthionine sulfoximine
(BSO)-mediated improvement in cultured embryo quality in vitro entails changes in ascorbate metabolism, meristem development and embryo maturation.
The researchers then repeated the experiment adding a drug inducing oxidative stress, buthionine sulfoximine
protects the viability of adult rat Leydig cells exposed to ethane dimethanesulfonate.