buspirone


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Related to buspirone: Wellbutrin

buspirone

 [bu-spi´rōn]
an antianxiety agent not related chemically to others; administered orally as the hydrochloride salt.

buspirone

(byo͞o-spī′rōn′)
n.
A drug, C21H31N5O2, used in its hydrochloride form to treat anxiety disorders.

buspirone

An anti-anxiolytic psychotropic agent of the azaspirodecanedione class, which is unrelated to benzodiazepines, barbiturates or other sedatives.
 
Adverse effects
Dizziness, insomnia, nervousness, drowsiness, lightheadedness, nausea, diarrhoea, headache, fatigue.

Warning
Avoid MAOIs when using buspirone.
 
Route
Oral and transdermal; initial adult dosage is 15 mg/day; maximum, 60 mg/day.
 
Mechanism of action
Buspirone has an affinity for both serotonin (5-HT1A) and dopamine (D2) receptors; its mechanism of action is currently unknown.

buspirone

Buspar® Neuropharmacology A psychotropic agent for managing anxiety and ADD. See Attention deficit disorder.

buspirone

A non-benzodiazepine antianxiety drug with slow onset of effect. A brand name is Buspar.

Buspirone

An antianxiety medication that is also given for withdrawal symptoms. It is sold under the trade name BuSpar.
References in periodicals archive ?
Buspirone is an azapirone anxiolytic agent that binds to both the serotonin and dopamine receptors in the brain.
(4-5) Augmentation agents, such as second-generation antipsychotics, lithium, thyroid hormone supplementation, buspirone, anticonvulsants, and combinations of antidepressants, may also be considered.
Standing doses of buspirone (30 mg) should be given every 8 hours.
Slangen, "The discriminative stimulus properties of buspirone involve dopamine-2 receptor antagonist activity," Psychopharmacology, vol.
Lithium was non-significantly less effective than all other augmentation agents except buspirone. Buspirone was non-significantly inferior to all other six augmentation agents.
Buspirone Hydrochloride was purchased from Sigma chemicals, Bangalore (India).
She was continued on this treatment and was discharged from the psychiatric inpatient unit on a combination of Lamotrigine 50mg twice a day Sertaline 150 mg daily and Buspirone 5mg twice daily.
Buspirone, serotoninergic anxiolytic and antidepressant, mediates its effect through the serotonergic system and the HPA axis.
Georgianna Gould, research assistant professor of physiology in the Graduate School of Biomedical Sciences and colleagues have shown that a medication called buspirone improved the social behaviors of mice.
Drugs: Diazepam ampoules (10 mg/2 ml; Hoffmann-La Roche, Basel, Switzerland) and buspirone hydrochloride (Sigma-Aldrich Co., St.
* The antidepressants buspirone (BuSpar), clomipramine (Anafranil) and sertraline (Zoloft)