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buprenorphine/bu·pre·nor·phine/ (bu″prĕ-nor´fēn) a synthetic opioid agonist-antagonist derived from thebaine, used as the hydrochloride salt as an analgesic and as an anesthesia adjunct.
A semisynthetic opioid drug, C29H41NO4, used usually in its hydrochloride form as an analgesic and, in combination with naloxone, for long-term treatment of addiction to opioids such as heroin.
a synthetic opioid agonist-antagonist derived from thebaine, used in the form of the hydrochloride salt as an analgesic for moderate to severe pain and as an anesthesia adjunct. Administered sublingually or by intramuscular or IV injection.
indications It is administered parenterally for the relief of moderate to severe pain and is used in tablet form to treat opioid dependence.
contraindication This Schedule V controlled substance is contraindicated for patients who may be opioid dependent.
adverse effects Among the reported adverse effects are respiratory depression, sedation, nausea, dizziness, vertigo, headache, vomiting, miosis, diaphoresis, and hypotension.
buprenorphineA formulation of semi-synthetic opioid which may be superior to methadone in reducing heroin and cocaine abuse/dependence.
buprenorphineAddiction medicine An agent that may be superior to methadone in ↓ heroin and cocaine abuse Side effects Sedation, constipation. Cf Methadone.
buprenorphineA powerful painkilling drug that binds to the body's opioid receptors. It acts for 6–8 hours. Brand names are Subutex, Temgesic and Transtec.
an analgesic and opiate antagonist. Its analgesic effects are much greater and last much longer than those of morphine.