bupivacaine


Also found in: Dictionary, Acronyms, Wikipedia.
Related to bupivacaine: lidocaine

bupivacaine

 [bu-piv´ah-kān]
a local anesthetic, used as the hydrochloride for local infiltration, peripheral nerve block, and retrobulbar, subarachnoid, sympathetic, caudal, or epidural block.

bupivacaine

/bu·piv·a·caine/ (bu-piv´ah-kān) a local anesthetic, used as the hydrochloride for local infiltration, peripheral nerve block, and retrobulbar, subarachnoid, sympathetic, caudal, or epidural block.

bupivacaine

(byo͞o-pĭv′ə-kān′)
n.
A potent, long-acting anesthetic, C18H28N2, used for regional anesthesia in its hydrochloride form.

bupivacaine

A potent long-acting amide-class local anaesthetic with a 4–8 hour duration of action, which is doubled by adding adrenaline/epinephrine.

Adverse effects
• CNS toxicity—Nervousness, perioral tingling, tinnitus, tremor, dizziness, blurred vision and seizures, followed by drowsiness, loss of consciousness, respiratory depression and apnoea.
• Cardiotoxicity—Hypotension, bradycardia, arrhythmias and cardiac arrest.

bupivacaine

Marcaine® Anesthesiology A potent local anesthetic with a 4-8 hr duration of action, doubled by adding epinephrine. Cf Ropivacaine.

bupivacaine

A long-acting local anaesthetic drug often used for nerve blocks, especially in epidural anaesthesia during childbirth and for the control of postoperative pain. The drug is on the WHO official list. A brand name is Marcaine.
References in periodicals archive ?
The time course of systolic blood pressure, heart rate and respiratory rate during epidural analgesia was similar for bupivacaine and ropivacaine.
Keywords: Bupivacaine, Intrathecal administration, Orthopedic procedures, Tramadol, Post operative analgesia.
They concluded that intrapleural bupivacaine does not produce adequate analgesia for shoulder pain control after unilateral thoracotomy16 but in our study, mean pain score based on VAS in all measured time points (except 6 hours after surgery) was <the control group.
There was an indirect correlation between the dose of bupivacaine administered and the pain in uterine exteriorization (R= -0.
The sample size was calculated on the basis of a study which evaluated the efficacy of pre-incisional bupivacaine infiltration on post-operative pain relief after appendectomy.
In both the groups that received bupivacaine in either form, the TFA was significantly higher than control group, which did not receive any local anesthetic drug.
The ED [sub]50 and ED [sub]95 of intrathecal bupivacaine were calculated by a logistic regression model described by Khaw et al .
There are a few studies that evaluated the postoperative pain relief after application of bupivacaine during gynecological laparoscopy.
In obstetric patients in whom intrathecal hyperbaric bupivacaine was injected in the sitting position, EVE failed to increase the sensory block compared with CSE and single shot subarachnoid block (10).
KEY WORDS: Ambulatory labour analgesia, Epidural analgesia, Bupivacaine, Fentanyl, Tramadol.