The primary complain at the time of presentation was recorded as leukocoria in 13 eyes (68.4%), proptosis in 4 eyes (21.1%), decreased vision in 1 eye (5.3%) and buphthalmos
in 1 eye (5.3%).
Identification of three different truncating mutations in cytochrome P4501B1 (CYP1B1) as the principal cause of primary congenital glaucoma (Buphthalmos
) in families linked to the GLC3A locus on chromosome 2p21.
(1,2) The absence of anterior segment disorders like megalocornea, buphthalmos
, and other findings of anterior segment dysgenesis is the main difference between JOAG and other childhood glaucomas.
Fernandez, Waminal already has a condition called "buphthalmos
" or an unusually large eyeball.
Abstract: An approximately 10-year-old, female Congo African grey parrot (Psittacus erithacus erithacus) developed progressive, unilateral exophthalmos and buphthalmos
. Survey radiographs revealed a large, coelomic, soft tissue mass, which was confirmed on computed tomography scan.
Ocular involvement may present in the form of choroidal angioma, glaucoma, hemianopsia, or buphthalmos
(enlargement of the coating of the eye).
(6%) of the cases in which CFP was indicated is due to congenital anomalies like microphthalmos, anophthalmos and in the cases of the Buphthalmos
after the eye ball was removed surgically.
(1974) reported the occurrence of buphthalmos
caused by congenital glaucoma because of the interference of PPM with the drainage of aqueous humor in an inbred colony of rats of the WAG strain (YOUNG et al., 1974).
conjunctivitis, keratitis, lacerations of the eyelids, punctured wounds of eyelids, hyphema, sub-conjunctival lower eyelid abscess, bilateral prolapse of third eyelid, nodular conjunctival lesion after lumpy skin disease, foreign body in cornea, perforating corneal wounds and buphthalmos
refers to the typical appearance of the eye in primary congenital glaucoma (PCG) (see Figure 2), (22) a rare condition which usually appears at birth or within the first year of life, and accounts for between 0.01% and 0.04% of cases of total blindness.
KEY WORDS: GLC3A Primary congenital glaucoma Genetic linkage Buphthalmos
Some current manuals and general works on ophthalmology and neuroophthalmology do not indicate normative dimensions of the eyeball even when buphthalmos
and microphthalmos are described or oculoplastic matters are discussed [17-19].