bullous disease

bullous disease

A general term for any dermopathy characterised by the splitting of the epidermis into bullae, often covering large areas of the skin surface.

Aetiology of epidermal/dermal split
Autoimmune, lichenoid, mechanical, spongiotic.

bullous disease

Dermatology Any of a number of conditions characterized by the formation of bullae covering large portions of the skin surface; many BDs are immune-mediated and can be separated based on the location of the lesions. See Bullous pemphigoid, Pemphigus vulgaris.
References in periodicals archive ?
Recently, an international panel of experts, the International Bullous Disease Group, published new recommendations on the diagnosis and management of pemphigus in the Journal of the American Academy of Dermatology, and recommended the use of an anti-CD20 monoclonal antibody, such as MabThera combined with a tapering regimen of oral CS, as a first-line therapy option for moderate to severe pemphigus.
Recently an international panel of experts, the International Bullous Disease Consensus Group, provided new recommendations on the diagnosis and management of pemphigus which includes the use of an anti-CD20 monoclonal antibody (Rituxan) and corticosteroids as first line therapy options for moderate to severe pemphigus.
Linear IgA dermatosis is a rare autoimmune bullous disease, yet the most common autoimmune bullous disease in children.
Direct immunofluorescence (DIF) was consistent with a subepithelial bullous disease. DIF studies demonstrated linear IgA (4+) staining in the basement membrane zone.
Our case indicates that the development of blistering lesions during PUVA therapy may be suggestive sign of a bullous disease such as BP and it should be excluded with proper clinical and laboratory approaches immediately after withdrawal of PUVA therapy.
Validation of disease--specific Autoimmune Bullous Disease Quality of Life (ABQOL) and the Treatment Autoimmune Bullous Disease Quality of Life (TABQOL) questionnaires," Advances in Medical Sciences, vol.
Dapsone interruption due to hemolysis did not aggravate the bullous disease. Meanwhile, hemolysis and a drop in hemoglobin levels continued, so intravenous immunoglobulin (IVIG) was started (1 g/kg) for two days, after which the fever and hemolysis stopped.
Emphysema is defined by chronic abnormal inflammatory cell response resulting in destruction of small airway and alveolar walls, with coalescent destructive lesions producing larger cavities resulting in bullous disease.(1) This alveolar destruction results in lung parenchymal distortion, making superimposed processes, particularly pulmonary edema, difficult to accurately identify.
Three cases each of chronic bullous disease of childhood, pityriasis rosea, verruca plana and scabies were newly referred and they were all misdiagnosed by referring doctors.
Changes at the BMZ in psoriasis itself may be responsible for precipitating the bullous disease. The presence of chronic inflammation, trafficking of activated lymphocytes and abundance of antigen presenting cells in psoriasis could unmask, expose or alter BMZ antigens, giving rise to autoantibody production.
The patient had pemphigoid gestationis, also known as herpes gestationis, a rare autoimmune bullous disease of pregnancy and the puerperium.