Bull's Eye

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A common adjective referring to a rounded appearance, lesion, mass or pattern that is circumferentially rimmed by 2+ distinct densities or colours; the inner circle is often dark—or radiopaque—rimmed by a lighter—or radiolucent—ring that in turn is surrounded by a third, dark or radiopaque circle; the opposite—light-dark-light—has been called a doughnut pattern
Dermatology A bull’s eye pattern—of discrete, irregular, flat, dark red, purpuric macules with a central vesicle—is a characteristic finding in erythema multiforme, which is mediated by circulating immune complexes, and triggered by infections, drugs, or connective tissue disease. A bull’s-eye lesion is also a classic finding in Lyme disease and seen 1–3 weeks before the onset of arthritic symptoms
Endoscopy A finding in the gastrointestinal lumen, in which oedematous folds surround a central depression—mass lesion—with a central ulcer, a non-specific finding seen in solitary amebomas, actinomycosis, amyloidosis, appendiceal disease, and tuberculosis; single bull’s-eyes include submucosal carcinoid, primary carcinoma, Kaposi sarcoma, leiomyoma, leiomyosarcoma, lipoma, and lymphoma; multiple bull’s-eyes occur in metastases from primary breast, lung, and renal carcinoma, lymphoma, and mastocytosis
Herbal medicine, Homeopathy Calendula, see there, Calendula officinalis
Imaging
General bull’s eyes Bull’s-eyes similar to those seen by endoscopy are caused by centrally ulcerated lesions, suggestive of cancer, in which the central zone is hypodense—i.e., necrotic—implying a rapidly proliferating lesion that has outgrown its vascular supply and typically occur in metastastic foci of lung or colorectl cancer in the liver; multifocal bull’s-eyes are suggestive of melanoma; unifocal bull’s-eyes occur in cancers metastatic to the GI tract, benign or malignant smooth muscle tumours of the intestinal wall, Kaposi and other sarcomas, eosinophilic granuloma, and ectopic pancreatic tissue.
GI tract A bull’s eye appearance with the lumen of the intestine may indicate intussusception
Elasticity imaging Benign single cysts and multicystic lesions of the breast have a bull’s eye appearance, which is regarded as a relatively reliable indicator of benignancy
Ophthalmology Bull’s eye maculopathy A fundoscopic finding seen in chloroquine-induced retinopathy, in which a depigmented lesion surrounds the macula, surrounded by another ring of relative hyperpigmentation, with possible permanent loss of visual acuity. The term bull’s eye has also been used in reference to the ocular fundus in a case of pseudoexfoliation glaucoma
Pathology An uncommon histologic finding in breast carcinoma, in which vacuoles have a central spot that variably stains with Giemsa, H&E, or PAS, possibly a processing artifact
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Take a shot from this distance while aiming the arrow tip at the bull's-eye. When you release the string, the arrow will strike far above your aiming point.
While it's easy to love 3-D targets, you should probably also own something with a few bull's-eyes on it, like the (3) High Roller ($120) from Morrell Targets (morrelltargets.com).
A black, flat-topped post works well when aiming at a white target with a dark bull's-eye; we aim by placing the dark bull's-eye right on top of the dark post.
The spot RI reading and bull's-eye optic figure, along with the lack of parting and the blue coating on the flat bottom of this cabochon, made this imitation detectable even without advanced testing equipment.
Shopper Vantage Point: The best shelf placement for shoppers makes finding their items easy--again, the bull's-eye is this spot.
We couple synthetic tornado events and event-derived (Joplin, Missouri EF5) damage context with a spatial modeling approach to evaluate the expanding bull's-eye effect using the superposition of hypothetical tornado events atop varying development morphologies.
In terms of precision and accuracy, you need to hit the figurative bull's-eye with every single arrow.
As if to nail that point home, the 14-year-old Springfield girl had just thwacked an arrow straight into the bull's-eye at 40 yards on Sunday afternoon when she was asked how long she had been practicing archery.
HBO's "Game of Thrones" drew series highs as it kicked off its second season April 1, hitting a bull's-eye in the key male demo.
Jim Clark, pistolsmith and bull's-eye competitor bought them for 10 cents apiece.
Do my eyes deceive me, or is there another bull's-eye galaxy behind the first, located at the 1 o'clock position?
Using the marker, draw a bull's-eye pattern with the rings at about 1.5 centimeter (.5 inch) intervals.