buffer solution

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Related to buffer solution: buffer capacity


1. a homogeneous mixture of one or more substances (solutes) dispersed molecularly in a sufficient quantity of dissolving medium (solvent).
2. in pharmacology, a liquid preparation of one or more soluble chemical substances, which are usually dissolved in water. For names of specific solutions, see under the name.
3. the process of dissolving or disrupting.
4. a loosening or separation.

Preparation of Solutions. Formula for preparing solutions from a pure drug:

For example, to prepare 2000 mL of a 2 per cent solution from boric acid crystals, the proportion would be

Formula for preparing solutions from stock solutions:

For example, to prepare 1000 mL of a 2 per cent solution from a 4 per cent stock solution, the proportion would be
aqueous solution one in which water is used as the solvent.
BCG solution an aqueous suspension of bacille Calmette-Guérin for instillation into the bladder to activate the immune system in treatment of superficial bladder cancers. It reduces the risk of a subsequent bladder cancer developing, although the exact mechanism of action is unknown.
buffer solution one that resists appreciable change in its hydrogen ion concentration (pH) when acid or alkali is added to it.
colloid solution (colloidal solution) imprecise term for colloid (def. 3).
hyperbaric solution one having a greater specific gravity than a standard of reference.
hypertonic solution one having an osmotic pressure greater than that of a standard of reference.
hypobaric solution one having a specific gravity less than that of a standard of reference.
hypotonic solution one having an osmotic pressure less than that of a standard of reference.
isobaric solution a solution having the same specific gravity as a standard of reference.
isotonic solution one having an osmotic pressure the same as that of a standard of reference.
molar solution a solution in which each liter contains 1 mole of the dissolved substance; designated 1 M. The concentration of other solutions may be expressed in relation to that of molar solutions as tenth-molar (0.1 M), etc.
normal solution a solution in which each liter contains 1 equivalent weight of the dissolved substance; designated 1 N.
ophthalmic solution a sterile solution, free from foreign particles, for instillation into the eye.
saturated solution one in which the solvent has taken up all of the dissolved substance that it can hold in solution.
sclerosing solution one containing an irritant substance (sclerosing agent) that will cause obliteration of a space, as in sclerotherapy.
standard solution one that contains in each liter a definitely stated amount of reagent; usually expressed in terms of normality (equivalent weights of solute per liter of solution) or molarity (moles of solute per liter of solution).
supersaturated solution an unstable solution containing more of the solute than it can permanently hold.
volumetric solution one that contains a specific quantity of solvent per stated unit of volume.

buffer solution

A solution of a weak acid and its salt, e.g., carbonic acid, sodium bicarbonate, important in maintaining a constant pH, esp. of the blood.
See also: solution
References in periodicals archive ?
DURACAL buffer solution pH 1.68, with certificate (pack = 500 ml) - catalog number 238272 HAMILTON - 1 pack;
The electrochemical properties of monomers and the monomer mixture were investigated in a phosphate buffer solution containing 0.05 M NaDBS.
The scan rate study was carried out using CV of 20 [micro]mol [L.sup.-1] AML and 50 [micro]mol [L.sup.-1] ATOR in BR buffer solution (pH 4.0).
(2005) incubated hay or wheat grain using different ratios of rumen fluid/buffer solution and reported reduction in final pH of in vitro incubation related to the decreased amount of buffer solution, differently from the findings of this study.
Sh-AA-MBA was tested for the sustained release of a model drug 5-asa in buffer solution (pH = 1.5 [+ or -] 0.5) (similar to artificial gastric juice) for first 3 hours and then at pH 6.8 [+ or -] 0.5, similar to artificial intestinal liquid, for next 8 hour duration at 37[degrees]C.
Resveratrol group (n = 5): 5 ml buffer solution with lipid fraction + 1 ml FeCl2 + 1 ml 10 mM H2O2 + 50 L 20 mM resveratrol + 1 ml neutral buffer
The release of the drug DMA from a silicone matrix into a sodium phosphate saline buffer solution at 6.0 pH is dependent on several factors.
The researchers found they could produce threads up to 20 centimeters long by dripping the concentrated proteins onto the surface of a salty buffer solution. For reasons that aren't clear, the threads then form a film that can be drawn out and spun into a fiber, Negishi, Fudge and their colleagues report in the Nov.
The investigators measured the response of the biosensor as a function of selected organic solvents methanol, ethanol and isopropanol--containing the phosphate buffer solution, at pH 6.5, at 100 megavolts against a reference electrode.
Immediately after cleaning, rinse the sensor in water and allow the sensor to soak in tap water or a 7 pH buffer solution for a few minutes to allow the pH sensor to stabilize.
The device consists of three electrodes, a buffer solution, a piece of paper (or nitrocellulose) and a plastic dish.
After BSA adsorption measurements, the fibre was transferred to a pure buffer solution. No recovery of the initial Fres was observed, indicating that the BSA adsorption process was irreversible.