Arenobufagin, a
bufadienolide compound from toad venom, inhibits VEGF-mediated angiogenesis through suppression of VEGFR-2 signaling pathway.
Mckenzie RA, Franke FP, Dunster PJ (1987) The toxicity to cattle and
bufadienolide content of six Bryophyllum species.
2009) found that newly laid Bufo marinus (Marine Toad) eggs contained high levels of
bufadienolide (toxin), whereas midstage tadpoles had lower levels and that all stages beyond the egg decreased in toxin diversity.
New insecticidal
bufadienolide, bryophyllin C, from Kalanchoe pinnata.
An endogenous
bufadienolide inhibitor of sodium pump, marinobufagenin, has also been shown to be increased in HF, and its plasma concentrations seem to correlate with severity of disease (65).
2% (1 mg/ml) while the
bufadienolide fraction had no inhibitory effect in the investigated concentrations.
Mammalian
bufadienolide is synthesized from cholesterol in the adrenal cortex by a pathway that is independent of cholesterol side-chain cleavage.
Preliminary data suggest that the
bufadienolide content in the chewable tablets used in the present study was less than 0.
Structure and stereochemistry of bryophyllin-A, a novel potent cytotoxic
bufadienolide orthoacetate from Bryophyllum pinnatum.
2001) reported that all
bufadienolides having an orthoacetate and alpha-pyrone moiety showed strong insecticidal activity.
Welzel, An Approach to
Bufadienolides from Deoxycholic Acid.
pinnata showed the presence of
bufadienolides, terpenoids and flavonoids (Costa et al.
