Squamous cell carcinoma of the buccal mucosa
: an aggressive cancer requiring multimodality treatment.
Concept of Narrow radial forearm flap and bipaddleradial forearm flap have been described which significantly reduces donor site morbidity by primary closure of wound.7,8 Usually preferred for isolated subunit reconstruction like tongue, oral lining of cheek and floor of mouth, radial forearm flap has also been used as folded flap for full thickness cheek defects.9 Because of its reliability and versatility it has been used for various reconstructions like Scalp, forehead and nose providing thin pliable tissue with reasonable colour match.10-12 We have described a flap design resembling to shape of TETRIS (famous video game) and we believe that it can be used to cover three different subunits (upper and lower lips and buccal mucosa
This allows the segregation of different cell types during which we have recently published (23, 24) Accordingly the aim of this study was to improve on the development of tissue engineered buccal mucosa
for future clinical use by comparing a synthetic trilayer (PLA-PHBV-PLA) biodegradable alternative to human dermis and further to explore the use of beta-aminopropionitrile ([beta]-APN) as a lysyl oxidase inhibitor to reduce contraction in these grafts.
In conclusion, the concurrent use of double buccal mucosa
from a single graft or preputial grafts in complex penile urethral strictures is a new technique, with excellent results as regards voiding parameters and quality of life.
The tumor was removed completely, and the tissue defect on the buccal mucosa
was repaired with a splitthickness skin graft.
Caption: Figure 4: Photomicrograph of the section shows normal buccal mucosa
(Toluidine Blue 10x).
Clinical diagnosis, n (%) LKP ELKP EP Total (n = 175) (n = 23) (n = 10) (n = 208) Mouth floor 16 (9.1) 2 (8.7) -- 18 (8.7) Tongue 31 (17.7) 7 (30.4) 3 (30.0) 41 (19.7) Gingiva 53 (30.3) 4 (17.4) 2 (20.0) 59 (28.4) Buccal mucosa
44 (25.1) 8 (34.8) 4 (40.0) 56 (26.9) Palate 12 (6.9) 2 (8.7) 1 (10.0) 15 (7.2) Retro molar 19 (10.9) -- -- 19 (9.1) LKP, leukoplakia; ELKP, erythroleukoplakia; EP, erythroplakia.
Caption: Figure 3: Intraorally, the left buccal mucosa
shows absence of extension of lesion
The inclusion criteria were; (1) age more than 18 years, (2) Either gender, (3) having diagnosed Oral SCC (4) Malignant tumor of buccal mucosa
Other sites include the palate, lips, buccal mucosa
, gingiva, palatine tonsil, and floor of the mouth.
Out of 59 major salivary glands, parotid was involved in 48 (82.35%) followed by submandibular gland in 11 (14.10%) cases, whereas out of 19 minor salivary glands, palate was commonest site involved by 13 (16.66%), followed by buccal mucosa
03 (3.84%) cases.
The symptoms include prodromal fever, conjunctivitis, coryza, cough, and small spots with white or bluish-white centres on an erythematous base on the buccal mucosa
. "A red, blotchy rash appears on the third to seventh day after the prodromal symptoms appear.