brush border enzyme


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brush border enzyme

An enzyme produced by the cells of the villi and microvilli (brush border) lining the small intestine.
See also: enzyme
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Caption: Figure 1: Hypothetical model depicting the mechanism by which a brush border enzyme intestinal alkaline phosphatase (IAP) affects the intestinal microbiota, the release of bacterial LPS-induced inflammation, and the luminal content of ATP inhibiting the commensal bacteria of different origin.
The measurement of brush border enzyme activities offers an additional objective tool to evaluate the severity of the histological abnormalities in untreated coeliac patients [11].
However, in the current study, no differences in activity of these enzymes were found among treatments on the jejunal and ileal brush border enzyme activities.
Digestive enzymes are very important to metabolize the feed or food containing polypeptide chains in the intestine into simple amino acids and the transport of the amino acids in the intestine is mainly achieved by a brush border enzyme gGT (Smith et al., 1991) that supports the catalysis of the decomposition of adenosine triphosphate (ATP) into adenosine diphosphate (ADP) and a free phosphate ion that releases energy, which is used by the enzymes to drive other chemical reactions and to help in the transportation of amino acids (Cotgreave and Schuppe- Koistinen, 1994).
In one research were done by [4], demonstrated that the effect of cod liver oil feeding was increasing of intestinal alkaline phosphatase, as there was no change in the activity of another brush border enzyme, Sucrase, under these conditions, that is compatible with our research results.