brush border


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border

 [bor´der]
a bounding line, edge, or surface.
brush border a specialization of the free surface of a cell, consisting of minute cylindrical processes (microvilli) that greatly increase the surface area.
Brush border, characterized by closely packed microvilli. From Dorland's, 2000.
vermilion border the exposed red portion of the upper and lower lips.

brush bor·der

the apical epithelial surface bearing closely packed microvilli about 2 mcm long, such as occur on the cells of the proximal tubule of the nephron.
Synonym(s): limbus penicillatus
A specialized portion of the free or apical aspect of certain epithelial cells—e.g., of the GI tract—consisting of closely packed microvilli that facilitate absorption; brush border cells line the luminal surface of the intestine and proximal convoluted tubules of the kidneys; the BB contains absorptive microvilli and glycocalyx—which is rich in hydrolytic enzymes

brush border

Physiology A specialized portion of the free or apical aspect of certain epithelial cells–eg, of the GI tract, consisting of closely packed microvilli that facilitate absorption; brush border cells line the luminal surface of the intestine and proximal convoluted tubules of the kidneys; the BB contains absorptive microvilli and glycocalyx–which is rich in hydrolytic enzymes

brush bor·der

(brŭsh bōr'dĕr)
An epithelial surface bearing closely packed microvilli about 2 mcm long, such as occurs in the proximal tubule of the nephron.

brush border

see MICROVILLUS.
References in periodicals archive ?
Bacteria were not observed in the ectoperitrophic space or attached to the brush border of the MGT in sections examined by LM and TEM.
The active cap region of the ABO is composed of tall, mitochondria-rich cells with distinct brush borders at their apicies, surrounding a hemolymph-containing central sinus.
Furthermore, when 2 to 3 yr-old sheep were intraduodenally infused with a 30 mM glucose solution for 4 d, glucose transporter activity in brush border membrane vesicles increased 40 to 80-fold.
It has been suggested that the brush border cytoskeleton is responsible for the shape, stability and motility of microvilli, composed mainly of actin, myosin and filament binding proteins (Mooseker, 1985).
These discrepancies may be attributable to proteolytic degradation of trehalase in urine, although the stability of trehalase in the renal brush border membrane or urine is not clear.
Different pig phenotypes affect adherence of Escherichia coli to jejunal brush borders by K88ab, K88ac and K88ad antigen.
Diabetic Nephropathy Associated with a Decrease in Brush Border Villin Levels in Meprin Expressing Kidneys.
The brush border enzymes in the microvilli complete the last phase of digestion before the sugars are absorbed into the body.
This is in agreement with the study conducted by Mohamed et al., who reported increase in the diameter of PCTs of male albino rats exposed to lead acetate both pre- as well as post-natally.14 One of the reasons for increase in the diameter of PCTs may be the loss of brush border due to oxidative stress produced by lead.
Lactose which is digested by the brush border enzyme lactase is one of the poorly absorbed short-chain carbohydrates, often referred as FODMAPs (fermentable, oligo-, di-, monosaccharides and polyols).
The above statement is supported by the following: (1) Histological analysis of the cigarette smoking followed by MI (S+MI) group showed alterations in kidney structure such as proximal convoluted tubules (PCTs), swelling of the PCT cells with thinning of the epithelial lining, focal loss of the brush border of PCTs, and patchy glomerular retraction.