brush border


Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia, Wikipedia.

border

 [bor´der]
a bounding line, edge, or surface.
brush border a specialization of the free surface of a cell, consisting of minute cylindrical processes (microvilli) that greatly increase the surface area.
Brush border, characterized by closely packed microvilli. From Dorland's, 2000.
vermilion border the exposed red portion of the upper and lower lips.

brush bor·der

the apical epithelial surface bearing closely packed microvilli about 2 mcm long, such as occur on the cells of the proximal tubule of the nephron.
Synonym(s): limbus penicillatus

brush border

microvilli on the free surfaces of certain epithelial cells, particularly the absorptive surfaces of the intestine and the proximal convoluted tubules of the kidney.
A specialized portion of the free or apical aspect of certain epithelial cells—e.g., of the GI tract—consisting of closely packed microvilli that facilitate absorption; brush border cells line the luminal surface of the intestine and proximal convoluted tubules of the kidneys; the BB contains absorptive microvilli and glycocalyx—which is rich in hydrolytic enzymes

brush border

Physiology A specialized portion of the free or apical aspect of certain epithelial cells–eg, of the GI tract, consisting of closely packed microvilli that facilitate absorption; brush border cells line the luminal surface of the intestine and proximal convoluted tubules of the kidneys; the BB contains absorptive microvilli and glycocalyx–which is rich in hydrolytic enzymes

brush bor·der

(brŭsh bōr'dĕr)
An epithelial surface bearing closely packed microvilli about 2 mcm long, such as occurs in the proximal tubule of the nephron.

brush border

see MICROVILLUS.

brush border

a specialization of the free surface of a cell, consisting of minute cylindrical processes (microvilli) that greatly increase the surface area.

brush border enzymes
include maltase, lactase, α-dextrinase and peptidases. Deficiencies of these enzymes may be primary or, more often, secondary to other intestinal disease.
References in periodicals archive ?
Elimination of brush border membrane protein in urine caused by toxic alterations of the tubular cell.
Preferential protection of Domains II and III of Bacillus thuringiensis Cry1Aa toxin by brush border membrane vesicles.
This variation of cholesterol at the brush border site, before absorption, is associated with the total of cholesterol produced by the liver and dietary cholesterol.
Also occurred caveolae, smaller pits and pale small vesicles localized next to the apical brush border of microvillus as well as coated vesicles, smooth surface vesicles and great vesicles were seen.
WGA also labeled the brush border of the MGT epithelium, and TEM showed that NAG was localized to the sides and tips of the microvilli.
Goblet cells containing predominantly intestinal-type mucin were scattered throughout the lesion, and many of the columnar surface epithelial cells had a distinct brush border.
A/E pathogens typically reside on a pedestal on the surface of the host epithelial cell and ultimately cause severe disruption of the microvilli brush border (Figure lA).
Brush border were also strongly stained with PAS stain while distal convoluted tubule (DCT) stained lighter than proximal convoluted tubule (PCT) (Figure-1a).
001) with dominant tubular necrosis extended to distal parts of proximal tubules and epithelial cell dissociation with cast formation, loss of brush border in large parts of proximal tubules and tubular obstruction17.
Another explanation for synergism between these toxins is that the individual pores made by different toxins may act together and show higher toxicity than the individual pores in the brush border membrane of insect's midgut epithelium.
Membrane insertion of the Bacillus thuringiensis Cry1Ab toxin: single mutation in domain II block partitioning of the toxin into the brush border membrane.
The cue is the presence of glucose in the intestinal lumen and its interaction with sweet taste receptors in the brush border membrane (Mace et al.