High concentrations of inflammatory mediators can cause: * Infectious exacerbations and * More mucus production bacterial colonization, resulting from stagnation of * Increased recruitment of secretions inflammatory cells * Damage to or destruction of * Edema, or tissue swelling cilia * Bronchiospasm
, resulting in * Lung overinflation sudden narrowing of the airways * Suboptimal ventilation/ * Progressive lung tissue perfusion balance injury and destruction * Atelectasis, or collapsed * Destruction of cilia alveoli * Infectious exacerbations * Overall obstruction of airways * Bacterial colonization * Irreversible fibrosis, or scar tissue formation
Brevetoxins have less neurotoxic effect than do PSP toxins, but they are easily aerosolized and when inhaled can lead to respiratory infection, coughing, and bronchiospasms
. Exposure to the amnesic shellfish poison (ASP) toxin domoic acid can lead to seizures, coma, amnesia, and formation of lesions in the brain.