bronchial challenge

Also found in: Dictionary, Thesaurus, Legal, Encyclopedia.

Related to bronchial challenge: Bronchial Provocation Test

challenge

[chal´enj]

1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.

2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.

3. the administration of such a substance in order to assess for a response; called also provocation.

bronchial challenge (inhalational challenge) bronchial challenge test.

bronchial challenge, bronchial challenge test

a challenge test in which a nonspecific agent such as histamine or methacholine is applied to the bronchi and they are assessed for a bronchoconstriction reaction. Also called bronchial provocation. See inhalational challenge test.

bronchial challenge

Inhalation of antigens to detect allergic reactions; in a positive BC, the Pt's temperature and WBC count rise, and the FEV₁, and FVC fall within 4–12 hrs of inhalation

Mentioned in ?

References in periodicals archive ?

Results [median (range)] of allergen bronchial challenge performed immediately after exposure to formaldehyde or air-only and methacholine bronchial challenge performed 8 hr after exposure.

Effect of formaldehyde on asthmatic response to inhaled allergen challenge

Of the 247 attenders, one could not perform reproducible spirometry, one declined bronchial challenge, two had echocardiograph abnormalities and 26 had baseline [FEV.

Persistence of atopic effects on airway calibre and bronchial responsiveness in older adults

For the 765 children for whom both tests were obtained, 76 of 152 (50%) children who were positive in the BHR test also responded to the SPT, and 76 of 208 (37%) children with a positive SPT also responded to the bronchial challenge.

The relationship between air pollution from heavy traffic and allergic sensitization, bronchial hyperresponsiveness, and respiratory symptoms in Dutch schoolchildren

The Phase II trials will study approximately 150 ragweed-allergic patients utilizing nasal, conjunctival and bronchial challenge methodologies.

ImmuLogic announces additional milestone payment from Marion Merrell Dow

Spirometric tests and bronchial challenges were performed in the Respiratory Laboratory.

Urinary cotinine and exposure to parental smoking in a population of children with asthma