bronchial challenge


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Related to bronchial challenge: Bronchial Provocation Test

challenge

 [chal´enj]
1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.
2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.
3. the administration of such a substance in order to assess for a response; called also provocation.
bronchial challenge (inhalational challenge) bronchial challenge test.

bronchial challenge

Inhalation of antigens to detect allergic reactions; in a positive BC, the Pt's temperature and WBC count rise, and the FEV1, and FVC fall within 4–12 hrs of inhalation
References in periodicals archive ?
Allergen bronchial challenge. Each exposure to formaldehyde or air-only was immediately followed by an allergen inhalation challenge.
Because a small number of subjects had an increase in [FEV.sub.1] during the bronchial challenge, a constant of 0.43 was added to all calculated DRS measurements, eliminating negative slopes prior to logarithmic transformation [8].
Lung function and bronchial challenge. Lung function was determined using a pneumotachometer (Jaeger, Wurzburg, Germany).
In a 2004 crossover study, Kimata exposed 20 people with dust mite-allergic bronchial asthma and 20 healthy participants to methacholine in a baseline bronchial challenge test.
The subjects were required to have persistent asthma symptoms requiring 2 puffs per day of a short-acting [[Beta].sub.2]-agonist as rescue therapy, to have at least 10% diurnal variation in their morning and evening peak expiratory flow (PEF) rates, and to be responsive to adenosine monophosphate (AMP) bronchial challenge testing.
Spirometric tests and bronchial challenges were performed in the Respiratory Laboratory.