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bro·mo·de·ox·y·ur·i·dine (BrDu),

A compound that competes with uridine for incorporation in RNA and fluoresces in ultraviolet light; used in BrDu-banding.


A thymidine analogue which induces point mutations by tautomerisation. It is incorporated into DNA during the S-phase of the cell cycle, and used to study DNA replication, DNA synthesis by flow cytometry, and cell cycle and tumour kinetics.

bromodeoxyuridine (brō´mōdēoksyur´ədēn),

n a compound that competes with uridine for incorporation in ribonucleic acid.
References in periodicals archive ?
The prognostic value of proliferation indices: a study with in vivo bromodeoxyuridine and Ki-67.
At the end of the incubation, bromodeoxyuridine was added to a final concentration of 30 [micro]mol/L, and the cell culture was incubated for 60 min at 37[degrees]C under 95% air-5% C[O.
1) was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazoliumbromide (MTT) assay and bromodeoxyuridine (BrdU) incorporation.
To determine cell proliferation, we added bromodeoxyuridine (BrdU; 30 [micro]g/mL; 1%; Amersham Biosciences, Little Chalfont, Bucks, England) during the last 3 hr of culture.
The functional relationship between in vivo bromodeoxyuridine labeling index and Ki-67 proliferation index in human breast cancer.
Dioscorea composita or Increased bromodeoxyuridine Dioscorea villosa uptake and intracellular cAMP L (Dioscoreaceae) level in keratinocytes 14.
A comparison of the predictive power for survival in gtiomas provided by MIB-1, bromodeoxyuridine and proliferating cell nuclear antigen with histopathologic and clinical parameters.
UV-irradiated cells and non-irradiated cells were labeled with 20 mM bromodeoxyuridine (BrdU; Amersham, Buckinghamshire, UK) for 10 min in 15-mL conical tubes, and then harvested and fixed overnight at 4[degrees]C with 70% ethanol.
Bromodeoxyuridine (BrdU) was injected in vivo to label the proliferating cells at hippocampus, and morphometry was used to count the hippocampal neurons.
2005); b) by measurement of the incorporation of bromodeoxyuridine (BrdU), which was added to the incubation media for the last 4 hr of culture, and c) by measurement of testosterone secreted into the culture media over the 48-hr culture period.
Phytoheamagglutinin (PHA-P), Hoechst 33258, Bromodeoxyuridine (BrdU) and colchicine were obtained from Sigma Chemicals, USA.