brodifacoum poisoning

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brodifacoum poisoning

Poisoning caused by the ingestion of brodifacoum. Brodifacoun, a long-acting derivative of warfarin, is often found in rodenticides.


Hemorrhage is the most common side effect and may occasionally be life-threatening. Bleeding within the kidneys and urinary tract produces acute renal failure.


Because warfarin interferes with the liver's use of vitamin K to produce clotting factors, brodifacoum poisoning is treated with vitamin K, fresh frozen plasma, and supportive therapy.

See also: poisoning