This helped to avoid the delays in management caused by prolonged waiting times at the single specialized center that offered
breast conservation surgery in the region.
Despite this,
breast conservation surgery has become the gold-standard treatment for the majority of early breast cancer cases, with low local recurrence rates after effective multimodal therapy, and with proof of concept that has withstood the test of time.
This is a single institutional prospective non-randomised controlled trial done on patients with early breast cancer who underwent
breast conservation surgery and required adjuvant radiation therapy in our hospital, which is a tertiary care cancer hospital in South India.
Given that IORT may be used either as a RT boost in conjunction with EBRT or as a monotherapy following
breast conservation surgery, it is possible that QOL maybe impacted to varying degrees.
But a ten-year research project by researchers from Duke University in North Carolina has found that a less radical form of treatment -
breast conservation surgery - is more effective, the Daily Mail reported.
This is especially apposite to the current practice of neo-adjuvant therapy and
breast conservation surgery.
Of the 583 who underwent
breast conservation surgery and radiation therapy for DCIS, most received 50 Gy of radiation in 25 fractions, and 21% received a boost.
Breast conservation surgery remains an option in many cases of breast cancer diagnosed in high-risk predisposition gene carriers.
The reduction in tumour size also makes
breast conservation surgery feasible in certain cases.
Variability in re-excision following
breast conservation surgery. JAMA.