BRCA2(redirected from breast and ovarian cancer susceptibility gene, early onset)
BRCA2A gene on chromosome 13q12.3 that encodes a protein which, like BRCA1, is involved in maintenance of genome stability, especially the homologous recombination pathway for double-stranded DNA repair; like BRCA1, it carries a marked increase in the lifetime risk of breast and ovarian cancer.
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BRCA2Molecular oncology A tumor suppressor gene linked to breast and ovarian CA See Tumor suppressor gene.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.