breakthrough pain


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breakthrough pain

n.
Transient, severe pain occurring against a background of stable, persistent, adequately controlled pain.

breakthrough pain

a transient increase in pain intensity that occurs in patients with stable, baseline persistent pain.
(1) Severe intermittent cancer pain that does not respond to the usual modalities—e.g., opiates—and may require anesthetic procedures—e.g., nerve blocks—intraspinal infusions of analgesic medication, or neuroablation
(2) A transitory flareup of pain in the setting of chronic pain managed with opioids. Breakthrough pain is related to a tumour or effects of therapy, or rarely, neither

breakthrough pain

Oncology Severe intermittent cancer pain that does not respond to the usual modalities–eg, opiates; BP may require anesthetic procedures–eg, nerve blocks, intraspinal infusions of analgesic medication, or neuroablation

break·through pain

(brāk'thrū pān)
Discomfort, usually acute and severe, which is experienced by patients between the normal doses of a medication that generally controls or palliates such pain.
References in periodicals archive ?
A novel 12-week study, with three randomized, double-blind placebo-controlled periods to evaluate fentanyl buccal tablets for the relief of breakthrough pain in opioidtolerant patients with noncancer-related chronic pain.
In our previous study, the demand-only PCEA method was associated with a 35% breakthrough pain rate, which compares with 10% associated with PCEABI in this study.
The scope of breakthrough pain in clinical practice.
He reports taking only 3 to 4 rescue doses per week of oxymorphone, 5 mg, for breakthrough pain.
Oral transmucosal fentanyl citrate: randomized, double-blinded, placebo-controlled trial for treatment of breakthrough pain in cancer patients.
The results suggest that adding epidural epinephrine at the beginning of labor significantly reduced the need for extra anesthesia to manage breakthrough pain, noted Dr.
Our findings suggest that a loss of resistance to air is associated with a higher incidence of recurrent breakthrough pain among parturients who received combined spinal epidural analgesia for labour than a loss of resistance to saline.
They had used a variety of drugs to control breakthrough pain, including hydro morphone, oxycodone, hydrocodone, morphine, and fentanyl citrate.
Of the 197 patients who used the tablets for up to a year, 80% said they preferred them to the pain medication they took previously for breakthrough pain, said Dr.
Most of the 50 million Americans with chronic pain will have breakthrough pain, and many will seek ED care, Dr.
The buccal tablet is an effervescent formulation which is a fast, effective route of medication administration for breakthrough pain (Webster, 2006).
Fentora, a tablet, was approved a year ago only as a treatment for pain flare-ups, called breakthrough pain, in cancer patients.