Also found in: Dictionary, Thesaurus, Legal, Acronyms, Encyclopedia, Wikipedia.
Related to breakthrough pain: Breakthrough bleeding
Transient, severe pain occurring against a background of stable, persistent, adequately controlled pain.
a transient increase in pain intensity that occurs in patients with stable, baseline persistent pain.
(2) A transitory flareup of pain in the setting of chronic pain managed with opioids. Breakthrough pain is related to a tumour or effects of therapy, or rarely, neither
breakthrough painOncology Severe intermittent cancer pain that does not respond to the usual modalities–eg, opiates; BP may require anesthetic procedures–eg, nerve blocks, intraspinal infusions of analgesic medication, or neuroablation
break·through pain(brāk'thrū pān)
Discomfort, usually acute and severe, which is experienced by patients between the normal doses of a medication that generally controls or palliates such pain.