breakthrough dose

breakthrough dose

an as-needed dose of medication for sporadic worsening of pain; given to palliate breakthrough pain.

breakthrough dose

the dose of an analgesic required for the relief of breakthrough pain. Also called rescue dose.

break·through dose

(brākthrū dōs)
As needed dosage of medication for sporadic worsening of pain; given to palliate breakthrough pain.
References in periodicals archive ?
As pain escalates, the dose of long-acting morphine should be increased based on the breakthrough dose requirements.
NB: Continue to give breakthrough doses of short-acting morphine (10 mg) Example 2.
Morphine can either be increased in increments of 30% of the previous day's dose or by calculating requirements based on the preceding 24 hours breakthrough doses, as shown in the examples above.