branched-chain amino acids


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Related to branched-chain amino acids: BCAAs

branched-chain amino acids

Abbreviation: BCAA
The essential amino acids, leucine, isoleucine, and valine. “Branched-chain” refers to their chemical structure. They are therapeutically valuable because they bypass the liver and are available for cellular uptake from the circulation. Parenteral administration, alone or mixed with other amino acids, is thought to be beneficial whenever catabolism due to physiological stress occurs. Skeletal muscles use BCAAs for their anticatabolic effects.
See also: amino acid
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
In maple syrup urine disease, due to deficiency of branched-chain [alpha]-keto acid dehydrogenase, the degradation of the essential branched-chain amino acids leucine, valine, and isoleucine and their corresponding 2-ketoacids is impaired.
Nutraceutical effects of branched-chain amino acids on skeletal muscle.
Influence of paroxetine, branched-chain amino acids and tyrosine on neuroendocrine system responses and fatigue in humans.
Gandolfo et al., "Sodium phenylbutyrate decreases plasma branched-chain amino acids in patients with urea cycle disorders," Molecular Genetics and Metabolism, vol.
Fernstrom, "Branched-chain amino acids and brain function," Journal of Nutrition, vol.
(1998) Influence of paroxetine, branched-chain amino acids and tyrosine on neuroendocrine system responses and fatigue in humans.
The effects of acute branched-chain amino acids supplementation on prolonged exercise capacity in a warm environment.
Wang, "Catabolism of branched-chain amino acids in heart failure: insights from genetic models," Pediatric Cardiology, vol.
Mccarthy et al., "Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents," Pediatric Obesity, vol.
44-46; [http://bit.ly/lgNALYil), the authors did not mention a medical food made from the branched-chain amino acids L-Leucine, L-Valine, and L-Isoleucine, which was reviewed by the FDA for the dietary management of tardive dyskinesia (TD) in males.(1), (2) Although this product, "Tarvil," is no longer being manufactured, compounding pharmacies can make it using the same ratio of ingredients that was tested in the clinical trial.
Rich in leucine and other branched-chain amino acids, whey protein is beneficial for stimulating muscle protein synthesis and has a neutral taste, complementing the flavor of the food to which it is added.

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