brain-derived neurotrophic factor

(redirected from brain-derived growth factor)
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brain-derived neurotrophic factor

A small nerve growth factor encoded on chromosome 11p13, which promotes the survival, migration and differentiation of neuronal precursors in the peripheral and central nervous system, and supports survival of primary sensory neurones originating from the neural crest and ectodermal placodes that do not respond to nerve growth factor (NGF). BDGF participates in axonal growth, pathfinding and in modulating dendritic growth and morphology.
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