brain natriuretic peptide

Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.
Related to brain natriuretic peptide: Atrial natriuretic peptide, troponin, C-type natriuretic peptide

brain natriuretic peptide (BNP)

a hormone, originally isolated from porcine brain tissue, having biological effects similar to those of atrial natriuretic peptide and stored mainly in the myocardium of the cardiac ventricles. Blood levels of BNP are elevated in hypervolemic states, such as congestive heart failure and hypertension.

brain natriuretic peptide

An atrial natriuretic peptide-like brain peptide produced predominantly in the cerebral ventricles, which induces diuresis and is secreted in response to fluid overload, as occurs in congestive heart failure.


(pep'tid?) [ pept(ic) + -ide]
A compound containing two or more linked amino acids.

atrial natriuretic peptide

Abbreviation: ANP
Atrial natriuretic factor.

brain natriuretic peptide

B-type natriuretic peptide.

B-type natriuretic peptide

Abbreviation: BNP
A hormone secreted by the left or right ventricle of the heart Concentration of this peptide in the bloodstream rises during episodes of decompensated heart failure.
See: brain natriuretic peptide

cell-penetrating peptide

A peptide that readily crosses cell membranes and therefore can influence cellular functions or carry other molecules that can directly or indirectly perform the same tasks.

endogenous opioid peptide

Any of a group of more than 15 substances present in the brain, certain endocrine glands, and the gastrointestinal tract. They have morphine-like analgesic properties, behavioral effects, and neurotransmitter and neuromodulator functions. Included in this group of chemicals are endorphins, enkephalins, and dynorphin.

glucose-dependent insulinotropic peptide

A hormone released by cells in the upper gastrointestinal tract in response to sugary or fatty meals. It stimulates beta cells in the pancreas to secrete insulin.

immunodominant peptide

Any of the peptides having a strong affinity for binding with class I or II histocompatibility antigens and for stimulating a response by T lymphocytes. Immunodominant peptides are produced by antigen processing, are expressed on the surface of macrophages and other antigen-presenting cells, and may be useful both in desensitizing people to allergens and in vaccine production.
Synonym: immunodominant epitope

natriuretic peptide

Any peptide that stimulates the kidneys to excrete salt and water.

peptide YY

An appetite-regulating protein released by L cells of the mucosa of the gastrointestinal tract in response to a meal. It binds to cells in the arcuate nucleus of the brain, decreases the desire to eat, and creates a feeling of fullness.
References in periodicals archive ?
Human brain natriuretic peptide is a kind of B type natriuretic peptide and endogenous polypeptide which is extensively distributed in heart tissues such as atrium, vascular endothelial cell and ventricular myocytes and it is effective in improving hemodynamic function.
The brain natriuretic peptide (BNP) precursor is the major immunoreactive form of BNP in patients with heart failure.
Changes in production and metabolism of brain natriuretic peptide in rats with myocardial necrosis.
It was observed that the level of brain natriuretic peptide was not related to body weight (Graphic 1; p = 0.
Measurement of cardiac natriuretic hormones (atrial natriuretic peptide, brain natriuretic peptide, and related peptides) in clinical practice: the need for a new generation of immunoassay methods.
Brain natriuretic peptide-32: N-terminal six amino acid extended form of brain natriuretic peptide identified in porcine brain.
Key Words: brain natriuretic peptide, N-terminal probrain natriuretic peptide, cardiac surgery, intensive care
Treatment of heart failure guided by plasma aminoterminal brain natriuretic peptide (N-BNP) concentrations.
Comment: The test measures NT-proBNP, which is released when brain natriuretic peptide (BNP) is cleaved from its precursor, proBNP.