Adverse effects unique to ticagrelor include dyspnea and, in patients with
bradydysrhythmias, asymptomatic ventricular pauses.
Prophylactic lidocaine is no longer recommended because of an increased incidence of
bradydysrhythmias and associated asystole.
Clark, "
Bradydysrhythmias and atrioventricular conduction blocks," Emergency Medicine Clinics of North America, vol.
It is theoretically contraindicated to use MAP in cases of bradycardia and
bradydysrhythmias or in conditions in which increasing the refractory period of the SA or AV node would be contraindicated such as first, second, or third degree AV heart blocks, SA node exit blocks, sinus pauses, and sinus arrest.
Ipecac administration is relatively contraindicated following ingestion of cardiotoxic, highly vagomimetic plants that can cause nausea, vomiting, and bradycardia; often progressing to
bradydysrhythmias, conduction blocks, and ventricular tachydysrhythmias.