bovine amyloidotic spongiform encephalopathy

bovine amyloidotic spongiform encephalopathy

a prion disease of cattle resulting in amyloid plaques in the brain.
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The cattle TSEs include: a) typical BSE, which is the priori strain identified during the BSE epidemic in Europe during the 1980s; b) H-type BSE, which is an uncommon type that was originally found in France (12); and c) L-type BSE, also called bovine amyloidotic spongiform encephalopathy (BASE), which is a rare form of BSE first identified in Italy (13).
The absence of clinical signs in these older animals, the unusual distribution of [PrP.sub.TSE], together with amyloid plaques, and a Western blot pattern that differed from the stereotypic pattern seen in typical BSE left little doubt about the probability that a new "atypical strain" had been identified (bovine amyloidotic spongiform encephalopathy [BASE]).
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