bone morphogenetic protein-7

bone morphogenetic protein-7

A protein encoded by BMP7 on chromosome 20q13, which plays a key role in cartilage formation, osteoblast differentiation, renal development and repair, and induces the production of SMAD1.
References in periodicals archive ?
Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro .
On the basis of type, the global bone morphogenetic protein market is sub divided into recombinant bone morphogenetic protein-7 (rhBMP-7) and recombinant bone morphogenetic protein-2 (rhBMP-2).
Mariel Therapeutics is a clinical stage biopharmaceutical company focused on the clinical application of Bone Morphogenetic Protein-7 (BMP-7) in osteoarthritis, chronic kidney disease, and Alport's Syndrome.
Regeneration of articular cartilage chondral defects by osteogenic protein-1 (bone morphogenetic protein-7) in sheep.
Harris et al., "Expression of bone morphogenetic protein-7 mRNA in normal and ischemic adult rat kidney," The American Journal of Physiology--Renal Physiology, vol.
Cole et al., "Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions," The Journal of bone and joint surgery.
Bone morphogenetic protein-7 (BMP-7; also called osteogenic protein-1), is a member of the Transforming Growth Factor b (TGF-b) superfamily, which was originally isolated from bone (1-3).
M2 EQUITYBITES-July 8, 2014-Mariel Therapeutics to acquire Stryker's Bone Morphogenetic Protein-7 assets
M2 PHARMA-July 8, 2014-Mariel Therapeutics to acquire Stryker's Bone Morphogenetic Protein-7 assets
8 July 2014 - US clinical stage biopharmaceutical company Mariel Therapeutics Inc said it had agreed to buy medical technology firm Stryker Corp's (NYSE:SYK) bone morphogenetic protein-7 (BMP-7) assets for the potential treatment of osteoarthritis (OA), chronic kidney disease (CKD) and other organ fibrosis conditions, lupus, and obesity.
Recombinant transforming growth factors-[beta]1 induces endochondral bone in the baboon and synergizes with recombinant osteogenic protein-1 (Bone Morphogenetic Protein-7) to initiate rapid bone formation.
Paul Krebsbach, DDS and colleagues from the University of Michigan School of Dentistry in Ann Arbor used an adenovirus vector engineered to express bone morphogenetic protein-7 (BMP-7) to transduce human gingival or rat dermal fibroblasts.
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