bone metastasis

bone metastasis

A tumour found in bone. The clinical aphorism, a malignancy in bone in patients above age 35 is considered metastatic until proven otherwise.

Sites of origin
Breast, prostate, thyroid, kidney.
References in periodicals archive ?
6] The median survival of patients after development of bone metastasis is approximately two years and 20% of these patients live longer than 5 years.
Clinical and economic burden of bone metastasis and skeletal-related events in prostate cancer.
It also reviews key players involved in the therapeutic development for Bone Metastasis and special features on late-stage and discontinued projects.
Negative impact of bone metastasis on outcome in clear-cell renal cell carcinoma treated with sunitinib.
Objective: Bone metastasis is a common complication for breast cancer patients, affecting 70% of patients diagnosed at advanced stages.
8] did a clinicopathological audit of bone metastasis from different gynaecological malignancies.
Recent publications using modern imaging technologies have clearly pinpointed that BS grossly underestimates the true prevalence of bone metastasis.
Their findings suggest that microRNAs could be effective treatment targets for tackling bone metastasis aACAo and also may help doctors detect the cancer's spread to the bone, Kang said.
Contributed by surgeons, oncologists, and other medical specialists from the US, Australia, and the UK, chapters detail the clinical management of common metastases; metastasis biology, including in vitro investigations, in vivo modeling, genes that mediate metastasis organotropism, cancer invasion and metastasis from molecular and cellular perspectives, sympathetic nervous system regulation of metastasis, the role of long non-coding RNA in breast cancer metastasis, hematopoietic stem cells and bone metastasis, and microRNAs and the progression of colorectal cancer; and translational research in breast cancer metastases in bone, brain metastasis, surgical stress response and metastasis, and tumor-initiating cells and therapeutic implications.
The optimal cutoff value of CYFRA 21-1, CEA, and CA125 for diagnosing bone metastasis of lung cancer was 42.