bone marrow purging

bone marrow purging

The removal of subpopulations of cells—ideally residual tumour cells—from the bone marrow, which is key to successful transplantation of autologous hematopoietic stem cells for treating leukaemia.

Purging methods
Photodynamic therapy, pharmacologic, biophysical agents (laser photoirradiation or radioisotopes), immunologic agents.
References in periodicals archive ?
bone marrow purging techniques to eliminate contaminating tumor cells from the harvested marrow, different combinations of chemotherapeutic agents, and the addition of immunotherapy to the regimen.
Bone Marrow Purging and Processing: Progress in Clinical and Biological Research 33, Alan R.
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