Bone marrow ablation | definition of bone marrow ablation by Medical dictionary
bone marrow ablation
bone marrow ablation Radio- or chemotherapy-induced destruction of bone marrow harbouring (or potentially harbouring) malignant cells, which remain after the administration of systemic chemotherapy. The patient’s own stem cells are used to reconstitute the marrow.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
bone marrow ablation Oncology The destruction of BM with radiation or drugs
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive
Additional AEs observed in clinical studies were consistent with the known side effects of HSC and bone marrow ablation
with busulfan including SAEs of veno-occlusive disease.
In this procedure healthy blood stem cells home in to the bone marrow to regenerate the blood system of cancer patients following bone marrow ablation
through chemotherapy or radiation.
However, in a leukemia patient whose chemotherapy results in successful bone marrow ablation
, the bone marrow would be dark on an FLT PET scan.