myositis ossificans

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myositis

 [mi″o-si´tis]
inflammation of a voluntary muscle; called also initis.
myositis fibro´sa a type in which there is a formation of connective tissue in the muscle.
multiple myositis polymyositis.
myositis ossi´ficans myositis marked by bony deposits in muscle.
trichinous myositis that which is caused by the presence of Trichinella spiralis.

my·o·si·tis os·sif·'i·cans

ossification or deposit of bone in muscle with fibrosis, causing pain and swelling in muscles.

myositis ossificans

A term that is slowly being retired from the medical literature, largely in favour of heterotopic ossification, given that
(1) inflammation is not a necessary precursor for heterotopic ossification; and
(2) the ossification doesn’t always occur in muscle, but may occur in fascia, tendons, and other mesenchymal soft tissues.

Clinical forms, myositis ossificans
• Localised: linked to trauma.
• Generalised: now known as fibrodysplasia ossificans progressiva, which is often due to spontaneous mutation, resulting in autosomal dominant pattern of inheritance in the proband’s progeny.

myositis ossificans

Bone formed within muscle; localized MO is 2º to trauma resulting from a blow or muscle tearing; generalized MO is AD, often accompanied by aplasia of the thumb, great toe, or rarely other digits, in which the first 'tumor' occurs in the paravertebral or cervical region, followed by multiple ossifying tumors, forming calcifying bridges across muscles and joints resulting in massive rigidity and the Pt is turned into 'stone'. See Zoning phenomenon.

het·er·o·top·ic os·si·fi·ca·tion

(het'ĕr-ō-top'ik os'i-fi-kā'shŭn)
Growth of calcium deposits within soft tissue, usually at the site of a hematoma due to blunt trauma or in tissue atrophied due to central nervous system injury.
Synonym(s): myositis ossificans.

myositis ossificans

A rare, usually familial, inflammatory disease of muscle in which CALCIFICATION occurs followed by the formation of bony tissue within the affected muscles.