With our read-across method (Level 2), the combined HI was more strongly influenced by BDE-100 (assumed to be as potent as BDE-99, with a critical
body burden of 9,000 ng/kgbw) than by BDE-154 and -183 (assigned the reference value of BDE-153, 62,000 ng/kg), and it was least influenced by the higher-brominated congeners that were assigned the reference value of BDE-209 (425,000 ng/kg) (Figure 1).
This difference, however, was a product of the influence of histological section size rather than an inherently higher
body burden.
Biomonitoring has limitations, since it can be difficult to identify the primary source of exposures and it is rarely possible to predict health outcomes based on chemical
body burdens.
In general, the urinary cadmium level reflects the
body burden over long-term exposure before the development of kidney damage, and blood cadmium is considered an indicator of recent exposure (69).
These data would be used, along with PCB congener data, if any significant changes in contaminant
body burden of the MCRL workers aroused suspicion that contaminant loads were confounded by aspects of lifestyle.
These public health achievements show that reductions in the production, use and disposal of toxic chemicals, along with the destruction of toxic chemical stockpiles and reservoirs, can all decrease the
body burden of noxious materials in our children and in us.
Blood lead represents only 1-5% of the total
body burden of lead (4,17).
Risk perceived to be posed by
body burdens of lead is endogenous because parents are aware that they can influence it by reducing exposures, A, and by the use of medical treatment, M:
The Flint water poisoning is a more acute event that suddenly changes everything for a large number of unsuspecting people --infants, children, and adults of all ages --adding further to their underlying
body burden of lead and other toxic metals already accumulated over their lifetimes.
Sampling occurred in winter to minimize the influence of gametogenesis and spawning on contaminant
body burden (Jovanovich & Marion 1987, Ellis et al.
Tenders are invited for Conduct a biomonitoring program to assess
body burden of legacy contaminants and chemicals of emerging concern in susceptible Great Lakes populations in areas
9) We know from
body burden studies that the average American has at least one form of parabens stored in their body.
