Scientists have thus been forced to look for alternatives for donated blood, which are called artificial blood substitutes
, artificial haemoglobin or haemoglobin based oxygen carriers (HBOC).
The effect of blood substitute
on the Hitachi 917 measurement point data was examined in closer detail using a serum specimen with an alkaline phosphatase activity of 500 U/L.
Alliance Pharmaceutical in San Diego has created a blood substitute
made of synthetic chemicals called perfluorocarbons.
Chang and his numerous colleagues and contributors have been successful in condensing and centralizing basic information as well as the current developments in the area of blood substitutes
in a user-friendly and manageable manner, which is quite a feat considering the highly interdisciplinary nature of the field of blood substitutes
The use of Adenosine and GSH to modify hemoglobin was presented as a viable strategy for a new generation blood substitute
The company plans to pasteurize the hemoglobin, a process that reduces the risk that a blood substitute
will harbor disease-causing microbes.
This strategy was cited by the FDA as a strategy for a new generation hemoglobin based blood substitute
at an FDA meeting on April 29, 2008.
Several researchers, including Enrico Bucci of the University of Maryland School of Medicine in Baltimore, have developed ways of cross-linking human hemoglobin molecules into cell-free blood substitutes
(SN: 9/26/87, p.
HemoTech represents a second-generation blood substitute
that uses novel pharmacological cross-linking technology (with adenosine and reduced glutathione), developed by Texas Tech scientists, to prevent the toxic reactions of hemoglobin that have appeared in the first generation products mentioned in the JAMA article above.
com), a biopharmaceutical company focused on developing and commercializing the first viable human blood substitute
, will present at the EQUITIES 57th Anniversary Spring Conference to be held at the Princeton Club on April 18th, in New York City.
One advantage of freeze-drying for the medics -who sould have to carry the blood substitute
into the field - is that the removal of water reduces weight and increases compressibility, according to Alan Rudolph, Barbara Rudolph's husband and a chemist at the Naval Research Laboratory.
CEO Discusses HemoTech, Potentially the First Viable Human Blood Substitute