blood dyscrasia


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dyscrasia

 [dis-kra´zhah]
a condition related to a disease or pathologic state, usually referring to an imbalance of component elements. adj., adj dyscrat´ic.
blood dyscrasia a pathologic condition of the blood, usually referring to a disorder of the cellular elements of the blood.
plasma cell d's a diverse group of neoplastic diseases involving proliferation of a single clone of cells producing a serum M component (a monoclonal immunoglobulin or immunoglobulin fragment); the cells usually have plasma cell morphology, but may have lymphocytic or lymphoplasmacytic morphology. The group includes multiple myeloma, Waldenström's macroglobulinemia, the heavy chain diseases, benign monoclonal gammopathy, and immunocytic amyloidosis. Called also paraproteinemias and monoclonal gammopathies.

blood dys·cra·si·a

a diseased state of the blood; usually refers to abnormal cellular elements of a permanent character.

blood dyscrasia

A nonspecific term for a defect in the blood.

Agents causing blood dyscrasias
Antimetabolites (e.g., leucovorin, methotrexate); potassium-sparing diuretics (spironolactone, tocainide, phenytoin, valproic acid, mexiletine, methazolamide, acetazolamide, azathioprine), especially if combined with xanthine oxidase inhibitors (e.g., allopurinol).

blood dys·cra·si·a

(blŭd dis-krā'zē-ă)
A diseased state of the blood; usually refers to abnormal cellular elements of a permanent character.

blood dyscrasia

Any abnormality of the blood cells or of the clotting elements.

blood dys·cra·si·a

(blŭd dis-krā'zē-ă)
Diseased state of the blood; usually refers to abnormal cellular elements of a permanent character.
References in periodicals archive ?
(11) The authors noted that viral infection might lead to blood dyscrasia early in illness, and that oseltamivir has been associated with a small incidence of blood dyscrasia.
Etiology of Subhyaloid hemorrhage were noted as diabetes in 15 (50%) cases, valsalva retinopathy in 6 (20%) cases, trauma in 3 (10%) cases, idiopathic 2 (6.66%) cases, retinal artery macroaneurysm in 2 (6.66%) patients, blood dyscrasia in 1 (3.33%) patient and neovessels on disc secondary to branch retinal vein occlusion in 1 (3.33%) patient.
The reported cases, as well as a few others,(10,11) emphasize the need to consider nasal or nasopharyngeal bleeding when hematemesis of obscure cause is encountered, especially when a history of recent epistaxis, facial trauma, blood dyscrasia, anticoagulant treatment, liver malfunction, and previous dyspepsia is lacking.
Additionally, when compared with carbamazepine, oxcarbazepine has a lower risk of cardiotcodcity, neurotoxicity, and blood dyscrasia. Oxcarbazepine has fewer drug-drug interactions because of a lower degree of hepatic enzyme induction.
Blood dyscrasias. All types of sulfonylurea blood disorders have been reported but their occurrence is rare.