blockade


Also found in: Dictionary, Thesaurus, Legal, Financial, Acronyms, Encyclopedia, Wikipedia.
Related to blockade: Blockade runner, military blockade

blockade

 [blok-ād´]
1. in pharmacology, the blocking of the effect of a neurotransmitter or hormone by a drug.
2. in histochemistry, a chemical reaction that modifies certain chemical groups and blocks a specific staining method.
adrenergic blockade selective inhibition of the response to sympathetic impulses transmitted by epinephrine or norepinephrine at alpha or beta receptor sites of an effector organ or postganglionic adrenergic neuron. See also adrenergic blocking agent.
cholinergic blockade selective inhibition of cholinergic nerve impulses at autonomic ganglionic synapses, postganglionic parasympathetic effectors, or neuromuscular junctions. See also cholinergic blocking agent.
ganglionic blockade inhibition by drugs of nerve impulse transmission at autonomic ganglionic synapses; see also ganglionic blocking agent.
narcotic blockade inhibition of the euphoric effects of narcotic drugs by the use of other drugs, such as methadone, in the treatment of addiction.
neuromuscular blockade a failure in neuromuscular transmission that can be induced pharmacologically or result from any of various disturbances at the myoneural junction. See also neuromuscular blocking agent.
sympathetic blockade block of nerve impulse transmission between a preganglionic sympathetic fiber and the ganglion cell.

block·ade

(blok-ād'),
1. The occupation of receptors by an antagonist so that usual agonists are relatively ineffective.
2. Receptor blockade, blocking the effect of a hormone at the cell surface.
3. Arrest of nerve impulse conduction or transmission at autonomic synaptic junctions, autonomic receptor sites, or neuromuscular junctions by various means, most often pharmacotherapy.
4. Intravenous injection of large amounts of colloidal dyes or other substances to block reticuloendothelial cells (for example, phagocytosis is temporarily prevented).

block·ade

(blok-ād')
1. Isolation of an organ, tissue, or system from communication with orinfluence by external forces or events.
2. Receptor blockade, blocking the effect of a hormone at the cell surface.
3. Arrest of peripheral nerve conduction or transmission at autonomic synaptic junctions, autonomic receptor sites, or myoneural junctions by a drug.
4. The occupation of receptors by an antagonist so that usual agonists are relatively ineffective.

blockade

The use of a drug to occupy, seal, or otherwise render inoperative, a receptor for natural hormones or neurotransmitters.

Patient discussion about blockade

Q. what does a sun block cream do? and what are a UV rays?

A. It blocks out harmful Ultra violet rays from the skin as the previous entries have related; however it can also block your ability to produce vitamin D. If you live in a northerly area or one that receives limited sunlight, its recommended to get at least 15 minutes of sun a day (this is probably best done with minimal sunblock) and according to personnal sun sensitivity. Another thing to keep in mind is that sunblock works best if applied 20 minutes before sun exposure.

Q. my son is 5 and half yrs old.he is having veezing and 75%block in one nose because of adenod.is is curable he has taken steriods for one and half yrs but with not much relief for veezing. then we switched on to ayur medicines,where he had some pigmentation at some places in his body. so again we are back to allopathy. he has one nasal steriod spray now with few other medicines. in his last test, dr, said he has adenod about 75% blcok in one nose, he has prescribed medicines for one month. he has also said that a small surgery can be done to remove adenod. i would like to know how long this surgry wil take and how much of rest he wil have to take. and if this adenod is removed, wil his other problem like veezing be cured? indira rajesh

A. it's a pretty common surgery from what i remember. most of our family has any kind of nasal problem...sinusitis..adenoids...just name it. the surgery is entering through the mouth (under full sedation) and lasering/curetting - removed. it took about a week to recover , eating soft foods..and it worked!

More discussions about blockade
References in periodicals archive ?
If the blockade on Donbass were to remain for the rest of the year it would result in the Ukrainian economy losing $2.5 billion in foreign export income, and approximately 30,000 jobs being at risk throughout the country. 
The Israeli blockade which is reinforced by Egypt has diverse and complex repercussions especially from a humanitarian stand point.
The international law for wars gives legal footing for sea and air blockades, but also puts restrictions on these blockades in several declarations, conventions and protocols.
Beyond basic humanitarian concerns, the blockade severely limits Gaza's ability to rebuild its economy in the aftermath of the crisis.
At the grand strategic, when will the international community tolerate the imposition of a blockade, and when will states accept consequent interference with the navigational rights of vessels flying their flags?
Israel then called upon its small, but effective, navy to implement that blockade.
traditional law of naval blockade, which is a collection of
NAN reports that with the U.S economic blockade of Venezuela, all entities within the United States, whether individual or government, are prohibited from engaging in any economic, commercial or financial transaction with Venezuela.
But despite Qatar's clear record in the war on terrorism as exhibited by Doha's military intervention against ISIL, the country is still subjected to the blockade that continues to bite.
Synopsis: Perhaps more than all the campaigns of the Union armies, it was the Union naval blockade which, covering all major Southern ports along 3,500 miles of coastline for the duration of the war, was key to bringing down the Confederacy.
The police will continue to monitor the situation at Kampung Tasik Cunex in Gerik after authorities removed the blockade that was put up illegally by Orang Asli on state land.