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a vesicle, especially a bulla.
blood blister a vesicle having bloody contents, as may be caused by a pinch or bruise.
fever b's herpes febrilis.
water blister one with clear watery contents.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


1. A fluid-filled, thin-walled structure under the epidermis or within the epidermis (subepidermal or intradermal).
2. To form a blister with heat or some other vesiculating agent.
Farlex Partner Medical Dictionary © Farlex 2012


a. A local swelling of the skin that contains watery fluid and is caused by burning or irritation.
b. A similar swelling on a plant.
v. blis·tered, blis·tering, blis·ters
To cause a blister to form on.
To break out in or as if in blisters.

blis′ter·y adj.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.


A saccular skin vesicle filled with serous fluid, which separates the epidermis and/or dermis, and which may be linked to shearing forces caused by trauma, burn, or a vesicatory agent; a collection of serous fluid.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


 A skin vesicle filled with serous fluid, caused by burns, trauma, or by a vesicatory; a collection of serous fluid
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.


1. A fluid-filled thin-walled structure under the epidermis or within the epidermis (subepidermal or intradermal).
2. To form a blister with heat or some other vesiculating agent.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


1. A collection of fluid below or within the epidermis.
2. To form a blister.


The area should be cleansed with mild soap and a protective dressing applied. Unless a blister is painful or interferes with function because of its size, it should not be punctured. If puncturing is required, it should be done aseptically, with the skin left in place. A sterile pressure bandage should then be applied.


If infection develops, treatment is the same as for any other wound, including tetanus prophylaxis or booster as required.
Enlarge picture
BLOOD BLISTER: On the sole of the foot after cryotherapy for a plantar wart

blood blister

A small subcutaneous or intracutaneous extravasation of blood resulting from the rupture of blood vessels. See: illustration


A firm dressing should be applied with moderate pressure to prevent extravasation and hasten absorption of blood. In some cases it is desirable to puncture the wound aseptically and aspirate the contents.

calendar blister

A blister pack in which each dose of a medication is labeled with a specific day of the week (e.g., M, T, W) or of the month (1st, 2nd, 3rd) to encourage and assist with daily compliance with medication dosing.

fever blister

A vesicular rash usually appearing on the lips or mucous membrane of the mouth during another infectious illness. The rash is caused by herpes simplex virus.
See: cold sore

fly blister

A blister produced by application of cantharides to the skin.

friction blister

An inflamed blister that forms beneath the epidermis after vigorous or repeated rubbing of the skin, e.g., on the toes or heels during sports activities.
Medical Dictionary, © 2009 Farlex and Partners


A fluid-filled swelling occurring within or just under the skin, usually as a result of heat injury or unaccustomed friction. The fluid is serum from the blood and is usually sterile.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005


A fluid-filled, thin-walled structure under the epidermis or within the epidermis (subepidermal or intradermal).
Medical Dictionary for the Dental Professions © Farlex 2012

Patient discussion about blister

Q. What's the best treatment for a blister?

A. use a clean needle and poke a small hole right at the base, between normal skin and the blister. Push the blister down, allow it to drain completely and put a bandaid over it; don't ever rip off blister skin allow it to fall off or reattach naturally.

Q. What are the causes of viral blisters on the skin? For a few months now I've been having these hard viral blisters on my fingers. The only way to get rid of them is with freezed carbon. It does go away with that treatment- after a few weeks but then a new one appears. How can I prevent it from "attacking" again??

A. These viral blisters you are describing are caused by HPV (papilloma virus), and are very hard to get rid of without treatment with freezed carbon. Many of us have the virus but not everyone gets the actual infection. There is not a proved way of preventing from it to happen again after treatment, unfortunately..

More discussions about blister
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References in periodicals archive ?
With multiple medicines, it is difficult to know what tablets are in the blister. The user depends on the dispenser to put the correct medicine in the pack.
Red sores or blisters that burst and leave crusty, golden-brown patches could be impetigo.
That evening she showed her parents the blisters and they all realized it was bad.
The mum-of-one said they went to their GP, who gave them antibiotics, but the blisters were getting worse so they went toMorriston Hospital, inSwansea, on June 7.
A kiln atmosphere with no movement -most prevalent in electric kilns-can allow a saturation of volatile glaze materials resulting in blisters. Correction: In electric kilns an active venting system can circulate the kiln atmosphere.
However, wound cultures of blister fluid, rapid antigen testing for group A beta-hemolytic Streptococci, and viral culture or polymerase chain reaction testing for herpes simplex virus may be considered.
* After draining a blister, use an antibiotic ointment before putting shoes J back on to prevent infection.
Eliminating the need for cold-form foils also allows for a smaller blister footprint, up to 40-60% size reduction, and provides clear visibility of the tablet/capsule in the blister cavity.
Don't burst a blister. In a day or two, new skin will form underneath, the tissue fluid will be reabsorbed and the blister skin will dry and peel.
Considering that prices of application bottles alone can start at 20 cents each and a fully filled, sealed, weighed, labeled and boxed bottle can approach a dollar, this can quickly add up to significant savings if blisters are substituted.
Unfortunately there is no specific antidote to the chemicals in the sap but these blisters can be very painful indeed and so pain relief is essential.
Blisters are dome-shaped defects that may occur when a coated object is immersed in water, when water lies on a horizontal coated surface (as during and after a rain), or upon exposure to high humidity.