Blepharokeratoconjunctivitis (BKC) is a chronic, inflammatory eyelid margin disease with conjunctival and corneal involvement.
Given the results and EUA findings the diagnosis was staphylococcal hypersensitivity/chronic blepharokeratoconjunctivitis (BKC) secondary to meibomianitis, with corneal neovascularization and scarring [2, 3].
Investigations for the twins with blepharokeratoconjunctivitis. Full blood count (FBC), electrolytes urea and creatinine (EUC), calcium magnesium phosphate (CMP), liver function tests (LFT), C-reactive protein (CrP), immunoglobulin M (IgM), immunoglobulin G (IgG), herpes simplex virus (HSV), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), Treponema pallidum (TP) antibody test, tuberculosis (TB), antinuclear antibodies (ANA), anti-neutrophil cytoplasmic antibody (ANCA), erythrocyte sedimentation rate (ESR), white cell count (WCC), polymerase chain reaction (PCR), and Epstein-Barr encoding region in situ hybridization (EBER ISH).
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Nischal, "Visual Outcome and Corneal Changes in Children with Chronic Blepharokeratoconjunctivitis," Ophthalmology, vol.
Dart, "Blepharokeratoconjunctivitis in children: Diagnosis and treatment," British Journal of Ophthalmology, vol.
Cabrera, "Sub-tenon triamcinolone acetonide injections for topical medication intolerance in chronic blepharokeratoconjunctivitis," Cornea, vol.
Caption: FIGURE 1: Photographs of Twin 1 with blepharokeratoconjunctivitis before and after treatment over a 10-month period.