cytotoxic antibiotics

(redirected from bleomycin sulphate)

cytotoxic antibiotics

Antibiotic drugs used to treat cancer. These drugs are, in general, unsuitable for treating bacterial infections. Examples are doxorubicin (Caelyx), daunorubicin (Cerubidin), dactinomycin (Cosmegen Lyovax), epirubicin (Pharmorubicin) and idarubicin (Zavedos).
References in periodicals archive ?
Cells were then treated with either BLM (Bleomycin Sulphate Nippon Kayaku, Sanofi Aventis) at 0.1-100 mU/mL or 8-epi-[PGF.sub.2[alpha]] (BIOMOL Research Laboratories Inc., USA) in the range of concentrations [10.sup.-10]-[10.sup.-7] M previously detected in in vivo experiments [16].
The bleomycin sulphate formulation used was Blenoxane (Bristol-Myers Squibb, Bedfordview, South Africa), which is a mixture of glycopeptides containing approximately 69% bleomycin [A.sub.2] and 29% bleomycin [B.sub.2].